Mofezolac
Mofezolac
- CAS:
- 78967-07-4
- MF:
- C19H17NO5
- MW:
- 339.34
Suppliers by country/region
Company Type
Properties
- Melting point:
- 147.5℃
- Boiling point:
- 527.2±50.0 °C(Predicted)
- Density
- 1.250±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- DMSO: soluble
- form
- A solid
- pka
- pKa ~3.3(at 25℃)
- color
- White to off-white
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H317-H319
- Precautionary statements
- P280-P305+P351+P338
- Toxicity
- LD50 in male, female mice, male, female rats (mg/kg): 1528, 1740, 920, 887 orally; 275, 321, 378, 342 i.p.; 612, 545, 572, 510 s.c. (Satoh)
Use
Mofezolac is a new non-steroidal analgesic antiinflammatory agent introduced in Japan for the treatment of post-operative and post-traumatic pain, acute upper respiratory tract pain, osteoarthritis, and lumbago. In in vfim studies, mofezolac inhibits prostaglandin biosynthesis and platelet aggregation, reportedly through the inhibition of cyclooxygenase. In animal studies, mofezolac showed more potent suppression in various writhing models than agents such as ibuprofen, mefenamic acid and aspirin. Mofezolac also has a potent inhibitory activity on the algesic responses induced by the mechanical stimulus of the inflamed tissue. The ulcerogenic effect of mofezolac on the gastric mucosa is far weaker than that of indomethacin and other agents.
0 India supplier list of "Mofezolac"
- Product Name:Mofezolac
- Products Intro:Brand:ajchemicals | Product Number:JDH-34068 | Purity:95+%
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:Mofezolac
- Products Intro:Package: 10 g | CustNote: Reach out to us for more information about custom solutions.
- Company Type: Trader
- Country/Region: UNITED STATES
- Product Name:Mofezolac
- Products Intro:Purity: 99.29% | Package: 5mg;33USD|10mg;58USD|25mg;119USD | CustNote: REAGENT;FOR LABORATORY USE ONLY
- Company Type: Trader
- Country/Region: UNITED STATES
- Main Products: Compound Libraries,Noval Small Molecucles,Nature Compounds,Inhibitory Antibodies,Life science Kits
- Product Name:Mofezolac
- Products Intro:Purity: 85.0-99.8% | Package: 1g;1USD
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Methyl 3-amino-2-fluorobenzoate
- Product Name:Mofezolac
- Products Intro:CustNote: https://www.alfa-chemistry.com/cas_78967-07-4.htm
- Company Type: Reagent
- Country/Region: UNITED STATES
- Main Products: Active Pharmaceutical Ingredient (API),Insect Pheromone,Boronic Compounds,Material & Chemicals,Lipid Compounds
- Product Name:Mofezolac
- Products Intro:Package: 10 mg；100 mg；2 mg；200 mg；25 mg；5 mg；50 mg | CustNote: REAGENT;FOR LABORATORY USE ONLY
- Company Type: Reagent
- Country/Region: UNITED STATES
- Main Products: Compound Libraries,Noval Small Molecucles,Nature Compounds,Inhibitory Antibodies,Life science Kits
- Product Name:Mofezolac
- Products Intro:Package: 25g; 50g; 250g;100g; 500g; 1kg; 5kg; 10kg; 25kg
- Company Type: Trader
- Country/Region: UNITED STATES
- Main Products: active pharmaceutical ingredients (APIs),Intermediates,pharmaceutical excipients,veterinary chemicals,packaging materials
- Product Name:Mofezolac
- Products Intro:Purity: 98% | Package: 100mg, 5mg, 50mg, 10mg, 25mg
- Company Type: Trader
- Country/Region: CHINA
- Product Name:Mofezolac
- Products Intro:Purity: 95% | Package: $57.9/1mg;Bulk package | CustNote: 95%
- Company Type: Trader
- Country/Region: UNITED STATES
- Main Products: Chemicals and BioChemicals,Materials Science,ligands acting on targets,Proteins,Antibodies
- Product Name:Mofezolac
- Products Intro:Purity: 0.99 | Package: 100g;1kg;5KG;1KG
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Isopropyl alcohol,Polyvinyl chlorid,Dodecylbenzenesulphonic acid,Dimethyl Sulfoxide,Titanium Dioxide