Mosapride
Mosapride
- CAS:
- 112885-41-3
- MF:
- C21H25ClFN3O3
- MW:
- 421.89
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Company Type
Properties
- Melting point:
- 151-153°C
- Boiling point:
- 549.2±50.0 °C(Predicted)
- Density
- 1.272±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 13.52±0.46(Predicted)
- color
- White to Off-White
Safety Information
Use
Mosapride citrate, a new gastroprokinetic benzamide was introduced in Japan as Gasmotin for the relief of gastrointestinal symptoms in patients with chronic gastritis, gastro-oesophageal reflux, dyspepsia and post-surgery use. Mosapride is synthesized by final amidation between the corresponding benzoic acid, itself obtained in 3 steps from methyl 4-acetamido salicylate, and the appropriate 2-aminomethyl-morpholine. Mosapride is a 5-HT4 partial agonist without notable activity for D2, 5-HT1 , 5-HT2, alpha-1 and alpha-2 receptors. In dogs, mosapride was as potent as cisapride to stimulate antral and duodenal motility. In most of species including man, mosapride undergoes extensive cleavage to a N-debenzylated metabolite which retains partial 5-HT4 activity but has potent 5-HT3 antagonist activity.
1 India supplier list of "Mosapride"
- Product Name:Mosapride
- Products Intro:Brand:synzeal | Product Number:140818950
- Company Type: Trader
- Country/Region: Gujarat,INDIA
- Product Name:Mosapride
- Products Intro:Brand:pharmaffiliates | Product Number:PA132300000
- Company Type: Trader
- Country/Region: Haryana,INDIA
- Product Name:4-Amino-5-chloro-2-ethoxy-N-((4-(4-fluorobenzyl)-2-morpholinyl)methyl)benzamide
- Products Intro:Purity: 98% | Package: 1KG;1USD
- Company Type: Reagent
- Country/Region: CHINA
- Main Products: Nicotinamide riboside chloride,Curcumin,L(+)-Ascorbic acid,L-Glutamine,Stevioside Basic information
$1.00/ 1KG
- Product Name:4-Amino-5-chloro-2-ethoxy-N-((4-(4-fluorobenzyl)-2-morpholinyl)methyl)benzamide
- Products Intro:Purity: 0.98 | Package: 1kg,2kg,5kg,10kg,25kg
- Company Type: Trader
- Country/Region: CHINA
- Main Products: 2,7-ADA,2,4,6-Trichloroaniline,TRIMETHYLOXONIUM TETRAFLUOROBORATE,Zinc sulfide,5-HEXEN-1-OL