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Mozavaptan

Mozavaptan

CAS:
137975-06-5
MF:
C27H29N3O2
MW:
427.54

Properties

Melting point:
213 - 217°C
Boiling point:
543.0±50.0 °C(Predicted)
Density 
1.21±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
13.04±0.70(Predicted)
color 
White to Off-White

Safety Information

Use

Mozavaptan is an oral vasopressin V2 antagonist that has been launched in Japan for inappropriate antidiuretic hormone secretion syndrome (IADHS), an affliction manifesting as hyponatremia. It joins another nonpeptidic benzazepine, conivaptan, which corrects sodium and water imbalance by blocking the renal V2 receptor resulting in enhanced diuresis, thereby effectively increasing serum sodium concentration. While conivaptan inhibits both V1 and V2 receptors, mozavaptan is significantly more selective for V2 (IC50 of 14nM vs. 1.2 mM for V1).

1 India supplier list of "Mozavaptan"

  • Product Name:Mozavaptan 95%
  • Products Intro:Brand:Glrinnovations | OriginalID:GLR19.174643
  • Company Type: Trader
  • Country/Region: INDIA
  • Product Name:Mozavaptan
  • Products Intro:Brand:ajchemicals | Product Number:JDH-34116 | Purity:97%
  • Company Type: Trader
  • Country/Region: INDIA

    $0.00/ 25KG

  • Product Name:Mozavaptan
  • Products Intro:Purity: 99% | Package: 25KG
  • Company Type: Service provider
  • Country/Region: CHINA

    $2.00/ 1kg

  • Product Name:Mozavaptan
  • Products Intro:Purity: 99% | Package: 1kg;2USD
  • Company Type: Reagent
  • Country/Region: CHINA

    $10.00/ 1PCS

  • Product Name:Mozavaptan
  • Products Intro:Purity: 99% | Package: 1PCS;10USD
  • Company Type: Trader
  • Country/Region: CHINA
  • Product Name:Mozavaptan
  • Company Type: Service provider
  • Country/Region: CHINA
  • Product Name:Mozavaptan
  • Products Intro:Purity: >98% | Package: 500mg | CustNote: BOC Sciences also provides custom synthesis services for Mozavaptan.
  • Company Type: Trader
  • Country/Region: UNITED STATES
  • Product Name:Mozavaptan
  • Products Intro:Purity: 0.98 | Package: 1kg,2kg,5kg,10kg,25kg
  • Company Type: Trader
  • Country/Region: CHINA
  • Product Name:mozavaptan
  • Products Intro:Purity: 0.99 | Package: 1kg
  • Company Type: Trader
  • Country/Region: CHINA
  • Product Name:Mozavaptan
  • Products Intro:Purity: 0.99 | Package: 1kg,5kg,25kgs,200kgs;bulk
  • Company Type: Trader
  • Country/Region: CHINA

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