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Mozavaptan

CAS No.: 137975-06-5

Chemical Name:: Mozavaptan

Synonyms: CS-134;OPC31260l;OPC 31260;MOZAVAPTAN;Mozavaptan USP/EP/BP;Mozavaptan (OPC-31260);N-(4-(5-(Dimethylamino);OPC-31260; OPC31260L; OPC 31260;-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl);5-(Dimethylamino)-1-[4-(2-methylbenzamido)benzoyl]-2,3,4,5-tetrahydro-1H-benzazepine

CBNumber:: CB51388577

Molecular Formula:: C27H29N3O2

Molecular Weight:: 427.54

MOL File:: 137975-06-5.mol

MSDS File:: SDS

Modify Date:: 2023/9/5 12:02:44

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Mozavaptan Properties

Melting point	213 - 217°C
Boiling point	543.0±50.0 °C(Predicted)
Density	1.21±0.1 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
solubility	Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form	Solid
pka	13.04±0.70(Predicted)
color	White to Off-White

Mozavaptan Chemical Properties,Uses,Production

Description

Mozavaptan is an oral vasopressin V2 antagonist that has been launched in Japan for inappropriate antidiuretic hormone secretion syndrome (IADHS), an affliction manifesting as hyponatremia. It joins another nonpeptidic benzazepine, conivaptan, which corrects sodium and water imbalance by blocking the renal V2 receptor resulting in enhanced diuresis, thereby effectively increasing serum sodium concentration. While conivaptan inhibits both V1 and V2 receptors, mozavaptan is significantly more selective for V2 (IC50 of 14nM vs. 1.2 mM for V1).

Uses

Mozavaptan is a vasopressin-receptor antagonist. It is used in the treatment of congestive heart failure and hyponatremia.

Mozavaptan Preparation Products And Raw materials

Raw materials

Preparation Products

Mozavaptan Suppliers

Global( 136)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
A.J Chemicals	91-9810153283	New Delhi, India	6124	58	Inquiry
Hebei Mojin Biotechnology Co., Ltd	+8613288715578	China	12456	58	Inquiry
career henan chemical co	+86-0371-86658258 +8613203830695	China	29898	58	Inquiry
Hebei Guanlang Biotechnology Co., Ltd.	+86-19930503282	China	8822	58	Inquiry
Xiamen AmoyChem Co., Ltd	+86-592-6051114 +8618959220845	China	6387	58	Inquiry
BOC Sciences	+1-631-485-4226	United States	19553	58	Inquiry
Chongqing Chemdad Co., Ltd	+86-023-6139-8061 +86-86-13650506873	China	39916	58	Inquiry
CONIER CHEM AND PHARMA LIMITED	+8618523575427	China	49391	58	Inquiry
Neostar United (Changzhou) Industrial Co., Ltd.	+86-519-519-85557386	China	11506	58	Inquiry
SIMAGCHEM CORP	+86-13806087780	China	17367	58	Inquiry

Supplier	Advantage
A.J Chemicals	58
Hebei Mojin Biotechnology Co., Ltd	58
career henan chemical co	58
Hebei Guanlang Biotechnology Co., Ltd.	58
Xiamen AmoyChem Co., Ltd	58
BOC Sciences	58
Chongqing Chemdad Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
Neostar United (Changzhou) Industrial Co., Ltd.	58
SIMAGCHEM CORP	58

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3-Hydroxypyridine Pyrrolidine Indoline Isoquinoline Tolvaptan

Pidotimod Mozavaptan 2,3,4,5-Tetrahydro-1H-benzo[b]azepine 2,3,4,5-TETRAHYDRO-1H-BENZO[B]AZEPIN-5-YLAMINE N-{4-[(methylamino)methyl]phenyl}acetamide

4-amino-N-(2-ethylphenyl)benzamide 4-AMINO-N-ETHYL-N-PHENYLBENZAMIDE Mozavaptan Hydrochloride

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OPC 31260 MOZAVAPTAN 5-(Dimethylamino)-1-[4-(2-methylbenzamido)benzoyl]-2,3,4,5-tetrahydro-1H-benzazepine Benzamide, N-[4-[[5-(dimethylamino)-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]carbonyl]phenyl]-2-methyl- -2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl) N-(4-(5-(Dimethylamino) CS-134 OPC-31260; OPC31260L; OPC 31260 OPC31260l N-[4-[[5-(dimethylamino)-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]carbonyl]phenyl]-2-methyl- Mozavaptan USP/EP/BP N-[4-[5-(dimethylamino)-2,3,4,5-tetrahydro-1-benzazepine-1-carbonyl]phenyl]-2-methylbenzamide N-(4-(5-(Dimethylamino)-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)phenyl)-2-methylbenzamide Mozavaptan (OPC-31260) 137975-06-5 Inhibitors Pharmaceutical intermediate