Pidotimod
- CAS No.
- 121808-62-6
- Chemical Name:
- Pidotimod
- Synonyms
- Adimod;3-L-pyroglutaMyl-L-thiazolidine-4-carboxylic acid;Axil;Onaka;pgt/1a;PoliMod;Pidomod;PIDOTIMOD;Pidomomod;Pidolimod
- CBNumber:
- CB9745917
- Molecular Formula:
- C9H12N2O4S
- Molecular Weight:
- 244.27
- MOL File:
- 121808-62-6.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/6/18 13:53:09
Melting point | 194-198°C (dec.) |
---|---|
alpha | D25 -150° (c = 2 in 5N HCl) |
Boiling point | 663.0±55.0 °C(Predicted) |
Density | 1.53 |
storage temp. | Keep in dark place,Sealed in dry,2-8°C |
solubility | DMSO (Slightly, Heated), Methanol (Slightly, Heated), 5N HCl (Slightly) |
form | powder |
pka | 3.03(at 25℃) |
color | white to beige |
optical activity | [α]/D -135 to -155°, c = 1 in 6 M HCl |
Merck | 14,7419 |
InChI | InChI=1S/C9H12N2O4S/c12-7-2-1-5(10-7)8(13)11-4-16-3-6(11)9(14)15/h5-6H,1-4H2,(H,10,12)(H,14,15)/t5-,6-/m0/s1 |
InChIKey | UUTKICFRNVKFRG-WDSKDSINSA-N |
SMILES | S1C[C@@H](C(O)=O)N(C([C@@H]2CCC(=O)N2)=O)C1 |
CAS DataBase Reference | 121808-62-6(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302-H315-H319-H335 |
Precautionary statements | P261-P305+P351+P338 |
RTECS | XJ5426675 |
HS Code | 2934.10.9000 |
Toxicity | LD50 in mice and rats (mg/kg): >4000 i.v.; >4000 i.m.; >8000 i.p.; >8000 orally (Coppi) |
Pidotimod price More Price(4)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | SML1335 | Pidotimod ≥98% (HPLC) | 121808-62-6 | 50MG | ₹10825 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | SML1335 | Pidotimod ≥98% (HPLC) | 121808-62-6 | 250MG | ₹43613.93 | 2022-06-14 | Buy |
TCI Chemicals (India) | P2147 | Pidotimod | 121808-62-6 | 5G | ₹8000 | 2022-05-26 | Buy |
TCI Chemicals (India) | P2147 | Pidotimod | 121808-62-6 | 25G | ₹16300 | 2022-05-26 | Buy |
Pidotimod Chemical Properties,Uses,Production
Description
Pidotimod, a dipeptide immunomodulating agent, has been introduced as immunostimulant therapy in patients with cell-mediated immunosuppression during respiratory or urinary tract infections. Its mode of action on the immune system is by activation of T-lymphocytes via interleukin (IL)-2 stimulation and macrophages via activation of superoxide dismutase and chemotaxis. In mice, treatment with pidotimod causes significant increase in the natural killer cell activity that may play an important role in immunosurveillance against tumors and in physiological homeostasis. Pidotimod can reverse the immunosuppression caused by surgical stress and has antiinflammatory, antioxidant, and antiaging properties. It has also been reported to provide protection from bacterial infections in mice.
Chemical Properties
White Solid
Uses
Immunostimulant used in patients with cell-mediated immunodepression.
Pidotimod Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
AnalyticsStanza Inc | +91-7032031309 +91-7032031309 | Hyderabad, India | 227 | 58 | Inquiry |
Lewens Labs | +917043057100 | Gujarat, India | 30 | 58 | Inquiry |
JR Corporation | +91-9099076719 +91-7096568000 | Gujarat, India | 14 | 58 | Inquiry |
Allastir Private Limited | +91-9840051621 +91-9791039207 | Tamil Nadu, India | 15 | 58 | Inquiry |
TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
CAD Pharma Inc. | 91-80-41536439 | Karnataka, India | 123 | 58 | Inquiry |
Lewens Labs | 91-7043057100 | Gujarat, India | 5 | 58 | Inquiry |
Clearsynth Labs | 91-22-45045900 | Maharashtra, India | 3889 | 58 | Inquiry |
Cleargreens Pharmaceutical Private Limited | 91-79-40026035 | Gujarat, India | 13 | 58 | Inquiry |
Supplier | Advantage |
---|---|
AnalyticsStanza Inc | 58 |
Lewens Labs | 58 |
JR Corporation | 58 |
Allastir Private Limited | 58 |
TCI Chemicals (India) Pvt. Ltd. | 58 |
Pharmaffiliates Analytics and Synthetics P. Ltd | 58 |
CAD Pharma Inc. | 58 |
Lewens Labs | 58 |
Clearsynth Labs | 58 |
Cleargreens Pharmaceutical Private Limited | 58 |
Related articles
- Pidotimod: uses, Mechanism of action, and Pharmacokinetics
- Pidotimod is a synthetic dipeptide molecule (3-l-pyroglutamyl-l-thiazolidine-4carboxilic acid) endowed with immunomodulatory a....
- Jun 18,2024
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