N-OXALYL GLYCINE
N-OXALYL GLYCINE
- CAS:
- 5262-39-5
- MF:
- C4H5NO5
- MW:
- 147.09
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Company Type
Properties
- Density
- 1.638±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- deionized water: >10mg/mL
- form
- solid
- pka
- 2.83±0.20(Predicted)
- color
- White to off-white
Safety Information
- Symbol(GHS)
GHS07
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Signal word
- Warning
- Hazard statements
- H302
- Hazard statements
- H302
- Precautionary statements
- P264-P270-P301+P312-P501
- Precautionary statements
- P264-P270-P301+P312-P501
- Hazard Codes
- Xi,Xn
- Risk Statements
- 22
- WGK Germany
- 3
- HazardClass
- IRRITANT
Use
The jumonji domain-containing protein 2 (JMJD2) subfamily of histone demethylases have been shown to catalyze demethylation of the methylated forms of histone 3 lysine 9 (H3K9) and H3K36 in vitro and in cells. Because histone demethylases are implicated in certain diseases, including cancer, selective inhibitors are candidate anticancer agents as well as potential tools for elucidating the biological functions of JMJDs. N-Oxalylglycine, the amide analog of α-ketoglutarate, is a cell permeable inhibitor of α-ketoglutarate-dependent enzymes, including JMJD2A, JMJD2C, and JMJD2E (IC50s = 250, 500, and 24 μM, respectively). It can also inhibit the prolyl hydroxylase domain-containing proteins PHD1 and PHD2 with IC50 values of 2.1 and 5.6 μM, respectively.[Cayman Chemical]
1 India supplier list of "N-OXALYL GLYCINE"
- Product Name:N-Oxalylglycine
- Products Intro:Brand:sigma aldrich | Product Number:O9390 | Purity:≥98%(HPLC)
- Company Type: Trader
- Country/Region: INDIA
- Product Name:N-Oxalylglycine 95%
- Products Intro:Brand：Glrinnovations | OriginalID：GLR19.150922
- Company Type: Trader
- Country/Region: INDIA
- Product Name:N-Oxalylglycine
- Products Intro:Brand:clearsynth | Product Number:CS-M-05129
- Company Type: Trader
- Country/Region: INDIA
- Product Name:N-Oxalylglycine
- Products Intro:Brand:ajchemicals | Product Number:JDH-71337 | Purity:95%
- Company Type: Trader
- Country/Region: INDIA
- Product Name:N-Oxalylglycine；Oxalylglycine
- Products Intro:Package: 10 mg；100 mg；200 mg；25 mg；5 mg；50 mg；500 mg | CustNote: REAGENT;FOR LABORATORY USE ONLY
- Company Type: Trader
- Country/Region: UNITED STATES
- Product Name:N-OXALYL GLYCINE
- Products Intro:Purity: 95.0%-99.0% | Package: 1ASSAYS;6.05USD
- Company Type: Trader
- Country/Region: CHINA
- Product Name:N-OXALYL GLYCINE
- Products Intro:Purity: 99.9% | Package: 25kgs/Drum;200kgs/Drum | CustNote: FDA GMP CEP Approved Manufacturer
- Company Type: Trader
- Country/Region: CHINA
- Product Name:N-OXALYL GLYCINE
- Products Intro:Purity: 98% | Package: 1g,10g,25g,100g,500g,1kg
- Company Type: Trader
- Country/Region: CHINA
- Product Name:N-OXALYL GLYCINE
- Company Type: Trader
- Country/Region: CHINA
- Product Name:N-Oxalylglycine
- Products Intro:Purity: 0 | Package: 1g; 5g; 25g; 1kg; 5kg; 25kg | CustNote: 0
- Company Type: Trader
- Country/Region: CHINA