OMecaMtiv Mecarbil
OMecaMtiv Mecarbil
- CAS:
- 873697-71-3
- MF:
- C20H24FN5O3
- MW:
- 401.43
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Properties
- Melting point:
- 180℃
- storage temp.
- -20°C Freezer
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- color
- White to Off-White
- Water Solubility
- 40.25mg/L at 25℃
- LogP
- -0.531
Safety Information
- Symbol(GHS)
GHS08
- Signal word
- Danger
- Hazard statements
- H372-H370
- Precautionary statements
- P260-P264-P270-P314-P501-P260-P264-P270-P307+P311-P321-P405-P501
Use
Omecamtiv mecarbil significantly increases fractional shortening starting at 0.4 mM plasma concentrations in SD rats, sham animals and in rats with heart failure. In conscious dogs with myocardial infarction (MI-sHF), Omecamtiv mecarbil leads to a significant increase in wall thickening (25%), stroke volume (44%), cardiac output (22%) and left ventricular (LV) systolic ejection time (26%). In addition, Omecamtiv mecarbil also results in the decreases of some hemodynamic parameters including heart rate, mean left atrial pressure, and LV end-diastolic pressure. In conscious dogs with left ventricular hypertrophy (LVH-sHF), Omecamtiv mecarbil leads to similar and not statistically different effects on hemodynamic parameters.
0 India supplier list of "OMecaMtiv Mecarbil"
- Product Name: OMecaMtiv Mecarbil
- Products Intro:Purity: 95%~99% | Package: 1ASSAYS;1USD
- Company Type: Reagent
- Country/Region: CHINA
- Main Products: Nicotinamide riboside chloride,Curcumin,L(+)-Ascorbic acid,L-Glutamine,Stevioside Basic information
$1.00/ 1ASSAYS
- Product Name:Omecamtiv mecarbil;CK-1827452
- Products Intro:Purity: 99.62% | Package: 1 mg;1 mL * 10mM (in DMSO);10 mg;100 mg;2 mg;25 mg;5 mg;50 mg | CustNote: REAGENT;FOR LABORATORY USE ONLY
- Company Type: Trader
- Country/Region: UNITED STATES
- Main Products: Compound Libraries,Noval Small Molecucles,Nature Compounds,Inhibitory Antibodies,Life science Kits