OTX015
OTX015
- CAS:
- 202590-98-5
- MF:
- C25H22ClN5O2S
- MW:
- 491.99
Suppliers by country/region
Company Type
Properties
- Melting point:
- 220 °C
- Density
- 1.45±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- ≥24.6 mg/mL in DMSO; insoluble in H2O; ≥106 mg/mL in EtOH with gentle warming
- pka
- 10.05±0.26(Predicted)
- form
- powder
- color
- white to light brown
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H302-H315-H319-H335
- Precautionary statements
- P261-P305+P351+P338
- HS Code
- 2934.99.3900
Use
OTX015 inhibits the binding of BRD2, BRD3, and BRD4 to AcH4 with IC50 ranging from 92 to 112 nM, and inhibits the growth of a variety of human cancer cell lines with GI50 ranging from 60 to 200 nM. OTX015 results in rapid down-regulation of c-MYC expression, and show the synergistic anti-proliferative effects in combination with ALK inhibitors in ALKpos ALCL cell lines.
1 India supplier list of "OTX015"
- Product Name:OTX015
- Products Intro:Brand:sigma aldrich | Product Number:SML1605 | Purity:≥98%(HPLC)
- Company Type: Trader
- Country/Region: Bangalore,INDIA
- Product Name:OTX015 98% (HPLC)
- Products Intro:Brand：Glrinnovations | OriginalID：GLR19.030827
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:OTX-015
- Products Intro:Brand:ajchemicals | Product Number:JDH-35276 | Purity:98+%
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:OTX015
- Products Intro:Brand:tcichemicals | Product Number:O0482
- Company Type: Reagent
- Country/Region: New Delhi,INDIA
- Product Name:OTX015
- Products Intro:Purity: 98% | Package: 10MG;50MG;100MG,1G,5G,10G.100G
- Company Type: Reagent
- Country/Region: CHINA
- Product Name:OTX015
- Products Intro:Purity: 0.99 | Package: 5KG;1KG | CustNote: Have any requirements, pls contact sales@zetchem.com
- Company Type: Trader
- Country/Region: CHINA
- Main Products: pharmaceutical, agrochemical, speciality chemical and liquid crystal industries.
- Product Name:OTX015
- Products Intro:Purity: >98% | Package: 50mg | CustNote: BOC Sciences also provides custom synthesis services for OTX015.
- Company Type: Trader
- Country/Region: UNITED STATES
- Product Name: 6H-?Thieno[3,?2-?f]?[1,?2,?4]?triazolo[4,?3-?a]?[1,?4]?diazepine-?6-?acetamide, 4-?(4-?chlorophenyl)?-?N-?(4-?hydroxyphenyl)?-?2,?3,?9-?trimethyl-?, (6S)?-
- Products Intro:Purity: Min98% HPLC | Package: 1KG;1USD
- Company Type: Trader
- Country/Region: CHINA
$1.00/ 1KG
- Product Name:OTX-015
- Products Intro:Purity: 98.0%
- Company Type: Trader
- Country/Region: CHINA
- Product Name:OTX015
- Products Intro:Purity: 99.9% | Package: 25kgs/Drum;200kgs/Drum | CustNote: FDA GMP CEP Approved Manufacturer
- Company Type: Trader
- Country/Region: CHINA