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Pemoline
Pemoline
- CAS:
- 2152-34-3
- MF:
- C9H8N2O2
- MW:
- 176.17
Properties
- Melting point:
- 255-256°C
- Boiling point:
- 307.77°C (rough estimate)
- Density
- 1.2662 (rough estimate)
- refractive index
- 1.5570 (estimate)
- storage temp.
- Store at RT
- solubility
- DMSO: soluble28mg/mL
- form
- solid
- pka
- pKa 10.5 (Uncertain)
- color
- white
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H302+H312+H332
- Precautionary statements
- P261-P264-P280-P301+P312-P302+P352+P312-P304+P340+P312
- Hazard Codes
- Xn,C,F,T
- Risk Statements
- 22-34-11-20/21/22
- Safety Statements
- 16-26-36/37/39-45-36/37-36
- WGK Germany
- 3
- RTECS
- PB8750000
- Toxicity
- LD50 orally in rats: 500 mg/kg (Schafer)
Use
Pemoline, 2-amino-5-phenyl-4(5H)-oxazolone (Cylert), hasa unique structure.The compound is described as having an overall effect onthe CNS like that of methylphenidate. Pemoline requires 3to 4 weeks of administration, however, to take effect. A partialexplanation for the delayed effect may be that one of theactions of the agent, as observed in rats, is to increase therate of synthesis of DA.
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