Prilocaine
Prilocaine
- CAS:
- 721-50-6
- MF:
- C13H20N2O
- MW:
- 220.31
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Properties
- Melting point:
- 37-38°
- Boiling point:
- bp0.1 159-162°
- Density
- 1.0117 (rough estimate)
- refractive index
- nD20 1.5298
- storage temp.
- 2-8°C
- solubility
- Slightly soluble in water, very soluble in acetone and in ethanol (96 per cent).
- pka
- pKa 7.32 or 7.89 (Uncertain)
- form
- Solid
- color
- White to off-white
- Water Solubility
- 6.169g/L(25 ºC)
- InChI
- InChI=1S/C13H20N2O/c1-4-9-14-11(3)13(16)15-12-8-6-5-7-10(12)2/h5-8,11,14H,4,9H2,1-3H3,(H,15,16)
- InChIKey
- MVFGUOIZUNYYSO-UHFFFAOYSA-N
- SMILES
- C(NC1=CC=CC=C1C)(=O)C(NCCC)C
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H302-H319
- Precautionary statements
- P301+P312+P330-P305+P351+P338
- HS Code
- 2924296000
Use
Prilocaine metabolism has beenstudied extensively in animal models, less is known aboutthe human metabolites or the human CYP enzymes involvedin their formation . The metabolism of prilocainein the liver yields o-toluidine, which is a possiblecarcinogen. Many aromatic amines, including o-toluidinehave been shown to be mutagenic, and metabolites of otoluidinehave been shown to form DNA adducts.Metabolites of o-toluidine are also believed to be responsiblefor the methemoglobinemia observed with prilocaineuse. To decrease the potential for methemoglobinemia, strictadherence to the maximum recommended dose should befollowed. Metabolism of prilocaine is extensive with lessthan 5% of a dose excreted unchanged in the urine.
54 India supplier list of "Prilocaine"
- Product Name:Prilocaine
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: INDIA
- Product Name:Prilocaine free base USP
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: INDIA
- Product Name:Prilocaine
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: INDIA
- Product Name:Prilocaine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: INDIA
- Product Name:Prilocaine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: INDIA
- Product Name:Prilocaine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: INDIA
- Product Name:Prilocaine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: INDIA
- Product Name:Prilocaine
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: INDIA
- Product Name:Prilocaine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Manufacturer
- Country/Region: INDIA
- Product Name:Prilocaine
- Products Intro:Purity: 99% | Package: Kg to Mtons
- Company Type: Reagent
- Country/Region: INDIA