Quetiapine fumarate
Quetiapine fumarate
- CAS:
- 111974-72-2
- MF:
- C25H29N3O6S
- MW:
- 499.58
Suppliers by country/region
- India(206)
- CHINA(257)
- United States(61)
- United Kingdom(15)
- Canada(9)
- Europe(2)
- The Netherlands(2)
- Russia(2)
- Czech(1)
- South Korea(5)
- Germany(9)
- Italy(3)
- Indonesia(1)
- Philippines(1)
- Mexico(2)
- Slovenia(1)
- Israel(2)
- Spain(12)
- Czech Republic(1)
- France(2)
- Brazil(4)
- Hungary(1)
- Finland(2)
- Switzerland(1)
- United Arab Emirates(1)
- Poland(1)
- Japan(1)
- Uruguay(1)
- Greece(1)
- Belgium(1)
- Nepal(1)
Company Type
Properties
- Melting point:
- 174-176°C
- Flash point:
- 9℃
- storage temp.
- 2-8°C
- solubility
- DMSO: >10mg/mL
- form
- powder
- color
- white to off-white
- Merck
- 14,8039
- BCS Class
- 2
- Stability:
- Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Safety Information
- Symbol(GHS)
GHS07,GHS09
- Signal word
- Warning
- Hazard statements
- H302-H400
- Precautionary statements
- P273-P301+P312+P330
- Hazard Codes
- Xn,N,T,F
- Risk Statements
- 22-50/53-52/53-39/23/24/25-23/24/25-11
- Safety Statements
- 60-61-45-36/37-16
- RIDADR
- UN1230 - class 3 - PG 2 - Methanol, solution
- WGK Germany
- 3
- RTECS
- KK3605000
- HS Code
- 29349990
Use
Quetiapine fumarate is an antipsychotic, successfully developed by the AstraZeneca United States, it interacts with a variety of neurotransmitter receptors, in the brain, it displays high degree affinity for serotonin (5-HT2) receptor, and it is greater than dopamine D1 and D2 dopamine receptor affinity in the brain. Quetiapine also has high affinity for histamine H1 receptor and adrenergic α1 receptors, and low affinity for α2 receptors, but it basically displays no affinity for cholinergic muscarinic receptors or benzodiazepine receptors . It shows positive results in antipsychotic activity assays such as conditioned avoidance reflex . In clinical, it is mainly used in treatment for adults with severe depression, acute manic episodes of bipolar disorder and schizophrenia of different types . It is not only effective for the positive symptoms of schizophrenia, but also having a certain effect for negative symptoms . It can also alleviate affective symptoms associated with schizophrenia, such as depression, anxiety symptoms and cognitive deficits. The above information is edited by the chemicalbook of Tian Ye.
206 India supplier list of "Quetiapine fumarate"
- Product Name:Quetiapine fumarate
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:Quetiapine fumarate
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg And 1MT
- Company Type: Manufacturer
- Country/Region: Gujarat,INDIA
- Product Name:Quetiapine fumarate
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Telangana,INDIA
- Product Name:Quetiapine fumarate
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Manufacturer
- Country/Region: Mumbai,INDIA
- Product Name:Quetiapine fumarate
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Manufacturer
- Country/Region: Gujarat,INDIA
- Product Name:Quetiapine fumarate
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: New Delhi,INDIA
- Product Name:Quetiapine fumarate
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg And 1MT
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA
- Product Name:Quetiapine fumarate
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Uttar Pradesh,INDIA
- Product Name:Quetiapine fumarate
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Telangana,INDIA
- Product Name:Quetiapine fumarate
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA