SB 203580
SB 203580
- CAS:
- 152121-47-6
- MF:
- C21H16FN3OS
- MW:
- 377.43
Suppliers by country/region
Company Type
Properties
- Melting point:
- 144-146
- Boiling point:
- 615.6±55.0 °C(Predicted)
- Density
- 1.4
- storage temp.
- -20°C
- solubility
- DMSO: 50 mg/mL
- form
- solid
- pka
- 9.60±0.10(Predicted)
- color
- white to off-white
- Stability:
- -200C
- InChIKey
- CDMGBJANTYXAIV-UHFFFAOYSA-N
Safety Information
- Symbol(GHS)
GHS05,GHS07
- Signal word
- Danger
- Hazard statements
- H302-H318
- Precautionary statements
- P264-P270-P280-P301+P312-P305+P351+P338-P501
- Hazard Codes
- Xn
- Risk Statements
- 22-41
- Safety Statements
- 26-39
- WGK Germany
- 3
- HS Code
- 29333990
Use
Water-soluble salt of SB 203580 (4-[5-(4-Fluorophenyl)-2-[4-(methylsulfonyl)phenyl]-1H-imidazol-4-yl]pyridine ). Selective inhibitor of p38 mitogen-activated protein kinase (IC 50 values are 50 and 500 nM for SAPK2a/p38 and SAPK2b/p38 2 respectively). Displays 100-500-fold selectivity over LCK, GSK3 and PKB . Shown to inhibit interleukin-2-induced T-cell proliferation, cyclooxygenase-1 and -2, and thromboxane synthase.
1 India supplier list of "SB 203580"
![](/images/pro-3.jpg)
- Product Name:SB203580-CAS152121-47-6-Calbiochem
- Products Intro:Brand:sigma aldrich | Product Number:559389 | Purity:SB203580,CAS152121-47-6,isahighlyspecific,potent,cell-permeable,selective,revers
- Company Type: Trader
- Country/Region: INDIA