Siccanin
Siccanin
- CAS:
- 22733-60-4
- MF:
- C22H30O3
- MW:
- 342.47
Suppliers by country/region
Company Type
Properties
- Melting point:
- 139-140°
- alpha
- D20 -136° (c = 2 in chloroform)
- Boiling point:
- 427.8±45.0 °C(Predicted)
- Density
- 1.18±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMF: Soluble; DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble
- form
- A solid
- pka
- 10.9(at 25℃)
Safety Information
- Toxicity
- LD50 in mice, rats (mg/kg): >6000, >1000 orally; >3000, >600 s.c. or i.p. (Suzuki)
Use
Siccanin is an unusual, fused, phenolic pentacycle first isolated from Helminthosporium siccans and reported in 1962 as a potent antifungal agent. Siccanin inhibits succinate dehydrogenase in the terminal electron transport system. More recent studies note the proximity of the siccanin binding site to the quinone-binding site of the enzyme. Species-selective inhibition by siccanin is unique among succinate dehydrogenase inhibitors and offers a lead for new chemotherapeutics.
0 India supplier list of "Siccanin"
- Product Name:Siccanin
- Products Intro:Purity: >98% by HPLC | CustNote: BOC Sciences also provides custom synthesis services for Siccanin.
- Company Type: Reagent
- Country/Region: UNITED STATES
- Product Name:Siccanin
- Products Intro:Purity: NLT 98% | CustNote: MC542641
- Company Type: Manufacturer
- Country/Region: CHINA
- Main Products: 2432-11-3,1052686-50-6,2198-53-0,3769-42-4,83647-42-1
- Product Name:Siccanin
- Products Intro:Purity: >=98% | Package: $172.9/500μg;$266.9/1mg;Bulk package | CustNote: 98%
- Company Type: Trader
- Country/Region: UNITED STATES
- Main Products: Chemicals and BioChemicals,Materials Science,ligands acting on targets,Proteins,Antibodies
-
500 μg$155.001 mg$279.00
- Product Name:Siccanin
- Products Intro:Brand: Caymanchem | Product Number: 23654 | Purity: >98%
- Company Type: Trader
- Country/Region: UNITED STATES
- Main Products: cof,mof
- Product Name:NSC135048
- Products Intro:Brand：dcchemicals | Product Number：DC36754
- Company Type: Trader
- Country/Region: UNITED STATES
-
1mg$456.005mg$1519.00
- Products Intro:Brand:1pchem | Product Number:1P00C48F | Purity:≥98%
- Company Type: Trader
- Country/Region: UNITED STATES
- Product Name:Siccanin
- Products Intro:Brand：aksci | Product Number：2290CB
- Company Type: Trader
- Country/Region: UNITED STATES
-
1mg$255.002.5mg$500.00
- Product Name:Siccanin
- Products Intro:Brand:trc-canada | Product Number:S497055
- Company Type: Trader
- Country/Region: CANADA
- Product Name:Siccanin
- Company Type: Trader
- Country/Region: UNITED STATES