Sitafloxacin
Sitafloxacin
- CAS:
- 127254-12-0
- MF:
- C19H18ClF2N3O3
- MW:
- 409.81
Suppliers by country/region
Company Type
Properties
- Boiling point:
- 629.2±55.0 °C(Predicted)
- Density
- 1.63±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMF: slightly soluble; DMSO: slightly soluble; Methanol: slightly soluble
- form
- A crystalline solid
- pka
- 6.39±0.50(Predicted)
Safety Information
Use
As a class, the major adverse events for fluoroquinolones are cardiac arrhythmia (due to QT interval 622 Shridhar Hegde and Michelle Schmidt prolongation), major phototoxicity, CNS disturbances (seizures, dizziness, and headaches), and tendonitis. The GI side effects, common to most antimicrobials, include Clostridium difficile-associated diarrhea (CDAD) and alterations in glucose homeostasis. From the clinical safety profile of sitafloxacin (1,059 patients receiving either 50 mg b.i.d. or 100 mg b.i.d.), about a third of patients experienced an adverse event with the most common being diarrhea, liver enzyme elevations, and headaches; however, the risk of QT prolongation, hypoglycemia, and hepatotoxicity were all considered to be low. Phototoxicity appears to be the limiting toxicity, particularly in non-Asian patients.
2 India supplier list of "Sitafloxacin"
- Product Name:Sitafloxacin
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:Sitafloxacin
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:7-((S)-7-Amino-5-azaspiro[2.4]heptan-5-yl)-8-chloro-6-fluoro-1-((1R,2S)-2-fluorocyclopropyl)-4-oxo-1,4-dihydroquinoline-3-carboxylicacid
- Products Intro:Brand:chemsworth | Product Number:158699020 | Purity:~97%
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:Sitafloxacin
- Products Intro:Brand:clearsynth | Product Number:CS-P-01147
- Company Type: Trader
- Country/Region: Hyderabad,INDIA
- Product Name:sitafloxacin
- Products Intro:Purity: 0.99 | Package: 1kg
- Company Type: Trader
- Country/Region: CHINA
- Product Name:Sitafloxacin
- Products Intro:Purity: 99% | Package: 1KG;7USD
- Company Type: Trader
- Country/Region: CHINA
$7.00/ 1KG
- Product Name:Sitafloxacin
- Products Intro:Purity: 99.9%|Package: 1g;1.1USD
- Company Type: Trader
- Country/Region: CHINA
$1.10/ 1g
- Product Name:SITAFLOXACIN
- Products Intro:Purity: 99% | Package: USP EP CP
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Pharmceutical,Optical Brightening,dyes
- Product Name:Sitafloxacin
- Products Intro:Purity: 0.99 | Package: 5KG;1KG
- Company Type: Trader
- Country/Region: CHINA
- Main Products: API(Active Pharmaceutical Ingredient),Lab Fine Chemical,Phytochemistry,Cosmetic Raw Materials
- Product Name:Spifloxacin
- Products Intro:Purity: 0.95&0.99 | Package: 0.1KG;1KG;1000KG | CustNote: Hot sales
- Company Type: Trader
- Country/Region: CHINA