SODIUM PROPIONATE
SODIUM PROPIONATE
- CAS:
- 6700-17-0
- MF:
- C3H5NaO2
- MW:
- 96.06
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Properties
- Melting point:
- 285-286 °C(lit.)
- solubility
- H2O: 0.1 g/mL, clear
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H312
- Precautionary statements
- P280
- Hazard Codes
- Xn
- Risk Statements
- 21
- Safety Statements
- 36/37
- WGK Germany
- 1
- RTECS
- UF7525000
- F
- 3
Use
As an excipient, sodium propionate is used in oral pharmaceutical formulations as an antimicrobial preservative. Like propionic acid, sodium propionate and other propionic acid salts are fungistatic and bacteriostatic against a number of Gram-positive cocci. Propionates are more active against molds than is sodium benzoate, but have essentially no activity against yeasts. Therapeutically, sodium propionate has been used topically in concentrations up to 10% w/w alone or in combination with other propionates, caprylates, or other antifungal agents, in the form of ointments or solutions for the treatment of dermatophyte infections. Eye drops containing 5% w/v sodium propionate have also been used. In food processes, particularly baking, sodium propionate is used as an antifungal agent; it may also be used as a flavoring agent in food products. In veterinary medicine, sodium propionate is used therapeutically as a glucogenic substance in ruminants.
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