Sofalcone
Sofalcone
- CAS:
- 64506-49-6
- MF:
- C27H30O6
- MW:
- 450.52
Suppliers by country/region
Company Type
Properties
- Melting point:
- 143-144°
- Boiling point:
- 478.6°C (rough estimate)
- Density
- 1.1362 (rough estimate)
- refractive index
- 1.4870 (estimate)
- storage temp.
- 2-8°C
- solubility
- Chloroform (Slightly), Ethyl Acetate (Slightly)
- form
- Solid
- pka
- 2.98±0.10(Predicted)
- color
- Light Yellow
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H302
- Precautionary statements
- P280-P305+P351+P338
- Toxicity
- LD50 in mice, rats: >10 g/kg orally (Tarumoto)
Use
Sofalcone is an anti-ulcer chalcone derivative. It blocks inflammation by suppressing the production of nitric oxide, TNF-α, and MCP-1 while inducing the expression of heme oxygenase-1 when used at 10-20 μM. Sofalcone (20-50 μM) induces VEGF expression in gastric epithelial cells and promotes gastric ulcer healing following eradication therapy for H. pylori.[Cayman Chemical]
3 India supplier list of "Sofalcone"
- Product Name:Sofalcone
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg And 1MT
- Company Type: Manufacturer
- Country/Region: INDIA
- Product Name:Sofalcone
- Products Intro:Brand:pharmaffiliates | Product Number:PA191640000
- Company Type: Trader
- Country/Region: INDIA
- Product Name:Sofalcone
- Products Intro:Purity: 99%|Package: 1kg;0.00;USD|25kg;0.00;USD
- Company Type: Trader
- Country/Region: CHINA
$0.00-0.00 / 1kg