Sparfloxacin manufacturers and suppliers in india

Sparfloxacin

Properties

Melting point:: 265°C

Boiling point:: 640℃

Density: 1.436±0.06 g/cm3(Predicted)

Flash point:: >110°(230°F)

storage temp.: Keep in dark place,Inert atmosphere,2-8°C

solubility: DMF: 10 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.50 mg/ml

pka: pKa1 6.25, pKa2 9.30(at 25℃)

form: powder

color: white to light yellow

Water Solubility: Soluble in DMSO at 9mg/ml. Sparingly soluble in water

BRN: 9170271

Safety Information

Symbol(GHS): GHS07

Signal word: Warning

Hazard statements: H315-H319-H335

Precautionary statements: P261-P264-P271-P280-P302+P352-P305+P351+P338

Hazard Codes: Xi

Risk Statements: 36/37/38

Safety Statements: 26-36

WGK Germany: 2

RTECS: VB1986500

HS Code: 29339900

Use

Sparfloxacin is the most potent fluoroquinolone antibiotic introduced for the treatment of community acquired infections. It has superior and broad in vitro activity against members of family Enterobacferiaceae and anaerobic bacteria, some of which are resistant to尾-lactam antibiotics or to aminoglycosides. In patients with surgical infections, sparfloxacin shows excellent activity against resistant pathogens. It is effective in treating patients with bladder irritability and is reported to have potential in the treatment of leprosy and Mycobacterium tuberculosis in mice. Favorable pharmacokinetic properties, good intracellular penetration and a lack of transferable resistance have been reported.