Spiramycin manufacturers and suppliers in india

Spiramycin

Properties

Melting point:: 126-128 °C

Boiling point:: 914℃

alpha: D20 -80° (methanol)

refractive index: 81 ° (C=2, 10% AcOH)

Flash point:: >110°(230°F)

storage temp.: 2-8°C

solubility: ethanol: 50 mg/mL, clear to slightly hazy, light-yellow

form: powder

color: white to light yellow

optical activity: [α]/D -85 to -80° in water (Specific rotation (dry basis))

Water Solubility: Soluble in methanol. Slightly soluble in water

Merck: 14,8752

Safety Information

Symbol(GHS): GHS07

Signal word: Warning

Hazard statements: H303

Precautionary statements: P270-P301+P312-P403-P501c

Hazard Codes: Xi

Risk Statements: 36/37/38

Safety Statements: 26-36-24/25

WGK Germany: 1

RTECS: WG9400000

F: 10

HS Code: 29419090

Toxicity: LD50 in rats (mg/kg): 9400 orally; 1000 s.c.; 170 i.v. (Sous)

Use

A fermentation product of Streptomyces ambofaciens, composed of several closely related compounds. Spiramycin 1 is the major component (c. 63%); spiramycins 2 and 3 are the acetate and monopropionate esters, respectively. It is available for oral administration and as spiramycin adipate for intravenous infusion. Spiramycins are relatively stable in acid conditions. A derivative, acetylspiramycin, is available in Japan.