Tegafur
Tegafur
- CAS:
- 17902-23-7
- MF:
- C8H9FN2O3
- MW:
- 200.17
Suppliers by country/region
Company Type
Properties
- Melting point:
- 171-173 °C(lit.)
- Density
- 1.3222 (estimate)
- storage temp.
- room temp
- solubility
- DMSO: >50mg/mL
- form
- Very Fine Crystalline Powder
- pka
- 7.63±0.10(Predicted)
- color
- white to off-white
- Merck
- 14,9112
- InChIKey
- WFWLQNSHRPWKFK-UHFFFAOYSA-N
Safety Information
- Symbol(GHS)
GHS06
- Signal word
- Danger
- Hazard statements
- H301+H311+H331
- Precautionary statements
- P261-P264-P280-P301+P310-P302+P352+P312-P304+P340+P311
- Hazard Codes
- T
- Risk Statements
- 23/24/25
- Safety Statements
- 22-36/37/39-45
- RIDADR
- UN 2811 6.1/PG 2
- WGK Germany
- 3
- RTECS
- YR0450000
- HazardClass
- 6.1
- PackingGroup
- II
- HS Code
- 29349990
- Toxicity
- LD50 in mice (mg/kg): 900 orally (3 days) (Yasumoto); 750 i.p. (FR 1574684), also reported as 1150 i.p. (Smart)
Use
Tegafur (INN, BAN, USAN) is a prodrug of Fluorouracil (5-FU), an antineoplastic agent used as the treatment of various cancers such as advanced gastric and colorectal cancers. It is a pyrimidine analogue used in combination therapies as an active chemotherapeutic agent in conjunction with Gimeracil and Oteracil, or along with Fluorouracil as Tegafur-uracil. Tegafur is usually given in combination with other drugs that enhance the bioavailability of the 5-FU by blocking the enzyme responsible for its degradation, or serves to limit the toxicity of 5-FU by ensuring high concentrations of 5-FU at a lower dose of tegafur.
12 India supplier list of "Tegafur"
- Product Name:Tegafur
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg And 1MT
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA
- Product Name:Tegafur
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Gujarat,INDIA
- Product Name:Tegafur
- Products Intro:Brand:sigma aldrich | Product Number:T7205 | Purity:≥98%(HPLC),powder
- Company Type: Trader
- Country/Region: Bangalore,INDIA
- Product Name:Ftorafur >99% (HPLC)
- Products Intro:Brand：Glrinnovations | OriginalID：GLR19.071109
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:Tegafur
- Company Type: Reagent
- Country/Region: Gujarat,INDIA
- Product Name:Tegafur
- Products Intro:Brand:clearsynth | Product Number:CS-O-11754
- Company Type: Trader
- Country/Region: Hyderabad,INDIA
- Product Name:Tegafur
- Company Type: Reagent
- Country/Region: Mumbai,INDIA
- Product Name:5-Fluoro-1-(tetrahydro-2-furfuryl)uracil
- Products Intro:Brand:tcichemicals | Product Number:F0635
- Company Type: Reagent
- Country/Region: New Delhi,INDIA
- Product Name:Tegafur
- Company Type: Reagent
- Country/Region: Maharashtra,INDIA
- Product Name:Tegafur
- Company Type: Reagent
- Country/Region: Mumbai,INDIA