URB597
URB597
- CAS:
- 546141-08-6
- MF:
- C20H22N2O3
- MW:
- 338.4
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Company Type
Properties
- Boiling point:
- 533.2±50.0 °C(Predicted)
- Density
- 1.23
- storage temp.
- 2-8°C
- solubility
- DMSO: ~14 mg/mL, soluble
- form
- powder
- pka
- 11.74±0.20(Predicted)
- color
- white
- Stability:
- Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
Safety Information
- Symbol(GHS)
GHS07,GHS09
- Signal word
- Warning
- Hazard statements
- H319-H410
- Precautionary statements
- P273-P305+P351+P338-P501
- Hazard Codes
- N
- Risk Statements
- 50/53
- Safety Statements
- 22-24/25-60-61
- RIDADR
- UN 3077 9/PG 3
- WGK Germany
- 3
Use
URB597 inhibits [3H]anandamide hydrolysis in rat brain membranes with a parallel increase in brain anandamide, OEA, and PEA content by inhibition of FAAH. URB597 enhances the hypothermia effect induced by ethanolamide by inhibiting FAAH.When delivered intraperitonealy (0.3 mg/kg) URB597 reduces allodynia and hyperalgesia through cannabinoid CB1 and CB2 receptor-mediated analgesia in rats with inflammatory pain.URB597 reduces the reduction in body weight gain and sucrose intake induced by the chronic mild stress in rats through inhibition of brain FAAH activity. URB597 could reverse most depressive-like symptoms induced by adolescent THC exposure in femal rats.
1 India supplier list of "URB597"
- Product Name:FAAHInhibitorII-CAS546141-08-6-Calbiochem
- Products Intro:Brand:sigma aldrich | Product Number:341249 | Purity:TheFAAHInhibitorII,alsoreferencedunderCAS546141-08-6,controlsthebiologicalactivi
- Company Type: Trader
- Country/Region: INDIA