ZAPRINAST
ZAPRINAST
- CAS:
- 37762-06-4
- MF:
- C13H13N5O2
- MW:
- 271.27
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Properties
- Melting point:
- 237-238°C dec.
- Density
- 1.48±0.1 g/cm3(Predicted)
- RTECS
- XZ6157358
- storage temp.
- Store at RT
- solubility
- 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 0.11 mg/mL
- form
- solid
- pka
- 6.92±0.20(Predicted)
- color
- white
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H315-H319-H335
- Precautionary statements
- P261-P264-P271-P280-P302+P352-P305+P351+P338
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36
- WGK Germany
- 3
Use
Zaprinast isYellow-Orange Crystalline Powder Zaprinast is a selective inhibitor of cyclic-GMP phosphodiesterase (PDE V, calmodulin insensitive). Since cGMP mediates the vasorelaxant action of nitric oxide, as well as the natriuretic and diuretic effect of at rial natriuretic factor (ANF) through the activation of PKG (cGMP dependent protein kinase), such inhibitors may display vasodilating, relaxant, and diuretic effects. These compounds may prove useful in treating hypertension and congestive heart failure.
0 India supplier list of "ZAPRINAST"
- Product Name:Zaprinast
- Products Intro:Brand:sigma aldrich | Product Number:Z0878 | Purity:solid
- Company Type: Trader
- Country/Region: Bangalore,INDIA