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Zaragozic acid A

ZARAGOZIC ACID A

CAS:
142561-96-4
MF:
C35H46O14
MW:
690.73

Company Type

Properties

alpha 
D22 +18.3° (c = 0.60 in CHCl3); D25 +37° (c = 1.29 in methanol)
Boiling point:
850.1±65.0 °C(Predicted)
Density 
1.35±0.1 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
Soluble in DMSO
form 
solid
pka
1.47±0.70(Predicted)
color 
white to light tan

Safety Information

WGK Germany 
3

Use

Zaragozic acid A is the major metabolite of a class of unusual bicyclic tricarboxylic acids, produced by a number of fungi in the genera Curvularia, Exserohilum, Setosphaeria and others, discovered at Merck and Glaxo in the early 1990s. In nature, zaragozic acid A acts as a broad spectrum antifungal but its mode of action as an inhibitor of squalene synthase, involved in sterol biosynthesis, led to investigation as a cholesterol lowering agent. Zaragozic acid A prepared by BioAustralis is presented as the free acid rather than the tri-sodium salt to avoid stability problems associated with hydrolysis of the salt.

0 India supplier list of "ZARAGOZIC ACID A"

  • Product Name:ZaragozicAcid
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  • Company Type: Trader
  • Country/Region: Haryana,INDIA
  • Product Name:Squalestatin A
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  • Products Intro:Purity: 95% | Package: $160.9/1mg;$398.9/5mg;Bulk package | CustNote: 95%
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  • Main Products: Chemicals and BioChemicals,Materials Science,ligands acting on targets,Proteins,Antibodies
  • 1 mg$159.00
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    5mg$706.00
  • Products Intro:Brand:1pchem | Product Number:1P009HEH | Purity:≥95%
  • Company Type: Trader
  • Country/Region: UNITED STATES
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  • Products Intro:Brand:trc-canada | Product Number:Z150605
  • Company Type: Trader
  • Country/Region: CANADA
  • Product Name:ZARAGOZIC ACID A
  • Company Type: Trader
  • Country/Region: UNITED STATES
  • Product Name:ZARAGOZIC ACID A
  • Company Type: Trader
  • Country/Region: UNITED STATES
  • Product Name:ZARAGOZIC ACID A
  • Company Type: Trader
  • Country/Region: SWITZERLAND

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