Zaragozic acid A
ZARAGOZIC ACID A
- CAS:
- 142561-96-4
- MF:
- C35H46O14
- MW:
- 690.73
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Properties
- alpha
- D22 +18.3° (c = 0.60 in CHCl3); D25 +37° (c = 1.29 in methanol)
- Boiling point:
- 850.1±65.0 °C(Predicted)
- Density
- 1.35±0.1 g/cm3(Predicted)
- storage temp.
- −20°C
- solubility
- Soluble in DMSO
- form
- solid
- pka
- 1.47±0.70(Predicted)
- color
- white to light tan
Safety Information
- WGK Germany
- 3
Use
Zaragozic acid A is the major metabolite of a class of unusual bicyclic tricarboxylic acids, produced by a number of fungi in the genera Curvularia, Exserohilum, Setosphaeria and others, discovered at Merck and Glaxo in the early 1990s. In nature, zaragozic acid A acts as a broad spectrum antifungal but its mode of action as an inhibitor of squalene synthase, involved in sterol biosynthesis, led to investigation as a cholesterol lowering agent. Zaragozic acid A prepared by BioAustralis is presented as the free acid rather than the tri-sodium salt to avoid stability problems associated with hydrolysis of the salt.
0 India supplier list of "ZARAGOZIC ACID A"
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- Product Name:ZaragozicAcid
- Products Intro:Brand:pharmaffiliates | Product Number:PA2630000
- Company Type: Trader
- Country/Region: Haryana,INDIA
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- Product Name:ZARAGOZIC ACID A
- Company Type: Trader
- Country/Region: SWITZERLAND