ZM 447439
ZM 447439
- CAS:
- 331771-20-1
- MF:
- C29H31N5O4
- MW:
- 513.59
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Company Type
Properties
- Melting point:
- 117-120°C
- Boiling point:
- 639.7±55.0 °C(Predicted)
- Density
- 1.282±0.06 g/cm3(Predicted)
- storage temp.
- Desiccate at RT
- solubility
- Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 25 mg/ml).
- form
- White solid
- pka
- 13.01±0.70(Predicted)
- color
- White
- Stability:
- Stable for 1 year from date of purchase? as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H315-H319
- Precautionary statements
- P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
Use
ZM 447439 is a selective and ATP-competitive inhibitor for Aurora A and Aurora B with IC50 of 110 nM and 130 nM, respectively. It is more than 8-fold selective for Aurora A/B than MEK1, Src, Lck and has little effect against CDK1/2/4, Plk1, Chk1, etc.
1 India supplier list of "ZM 447439"
![](/images/pro-3.jpg)
- Product Name:AuroraKinaseInhibitorVI,ZM447439-CAS331771-20-1-Calbiochem
- Products Intro:Brand:sigma aldrich | Product Number:189410 | Purity:TheAuroraKinaseInhibitorVI,ZM447439,alsoreferencedunderCAS331771-20-1,controlsth
- Company Type: Trader
- Country/Region: INDIA