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ChemicalBook > Product Catalogue >Biochemical Engineering >Chinese Herbs >10-Gingerol

10-Gingerol

10-Gingerol Structure
  • ₹25027.4 - ₹55759.58
  • Product name: 10-Gingerol
  • CAS: 23513-15-7
  • MF: C21H34O4
  • MW: 350.49
  • EINECS:
  • MDL Number:MFCD01682694
  • Synonyms:10-GINGEROL, HPLC 98%;10-GINGEROL;5-HYDROXY-1-(4-HYDROXY-3-METHOXYPHENYL)-3-TETRADECANONE;(5S)-1-(3-Methoxy-4-hydroxyphenyl)-5-hydroxytetradecane-3-one;(5S)-5-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-tetradecanone;(S)-1-(3-Methoxy-4-hydroxyphenyl)-5-hydroxytetradecane-3-one;(S)-12-Oxo-14-(3-methoxy-4-hydroxyphenyl)tetradecane-10-ol;(5S)-5-hydroxy-1-(4-hydroxy-3-methoxy-phenyl)tetradecan-3-one
3 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 5MG
  • 10MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberG5798
  • Product description[10]-Gingerol ≥98% (HPLC)
  • Packaging5MG
  • Price₹25027.4
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberG5798
  • Product description[10]-Gingerol ≥98% (HPLC)
  • Packaging10MG
  • Price₹31327.55
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number42630
  • Product description[10]-Gingerol analytical standard
  • Packaging10MG
  • Price₹55759.58
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) G5798 [10]-Gingerol ≥98% (HPLC) 5MG ₹25027.4 2022-06-14 Buy
Sigma-Aldrich(India) G5798 [10]-Gingerol ≥98% (HPLC) 10MG ₹31327.55 2022-06-14 Buy
Sigma-Aldrich(India) 42630 [10]-Gingerol analytical standard 10MG ₹55759.58 2022-06-14 Buy

Properties

Melting point :56-58 °C
Boiling point :499.7±35.0 °C(Predicted)
Density :1.037±0.06 g/cm3(Predicted)
Flash point :166℃
storage temp. :2-8°C
solubility :methanol: soluble5mg/mL, clear, colorless
form :Solid
pka :10.02±0.20(Predicted)
color :Yellow
Water Solubility :practically insoluble in water
InChIKey :AIULWNKTYPZYAN-SFHVURJKSA-N
LogP :4.900 (est)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

10-Gingerol is a phenol that has been found in Z. officinale and has diverse biological activities. It scavenges DPPH , superoxide, and hydroxyl radicals in cell-free assays (IC50s = 10.47, 1.68, and 1.35 μM, respectively) and inhibits oxidative burst induced by N-formyl-Met-Leu-Phe (fMLP; ) in isolated human polymorphonuclear (PMN) neutrophils when used at a concentration of 6 μM. 10-Gingerol inhibits NETosis and the production of reactive oxygen species (ROS) induced by LPS or lupus-relevant stimuli, including ribonucleoprotein-containing immune complexes and anti-phospholipid antibodies, in isolated human neutrophils. It is active against M. avium and M. tuberculosis (MICs = 25 and 50 μg/ml, respectively). 10-Gingerol (200 μM) is also cytotoxic to human MDA-MB-231 and MDA-MB-468 and murine 4T1 and EO771 mammary carcinoma cells.

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