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cyclopentyl 2-cyclohexyl-2-((6-(3-(hydroxyamino)-3-oxopropyl)pyridin-3-yl)methylamino)acetate

cyclopentyl 2-cyclohexyl-2-((6-(3-(hydroxyamino)-3-oxopropyl)pyridin-3-yl)methylamino)acetate Structure
Properties Safety Information Description
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

storage temp. :Store at -20°C
solubility :DMSO:81.0(Max Conc. mg/mL);200.73(Max Conc. mM)
Ethanol:15.0(Max Conc. mg/mL);37.17(Max Conc. mM) form :A crystalline solid
color :Light yellow to khaki

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

GSK3117391 is a histone deacetylase (HDAC) inhibitor (IC50 = <100 nM in HeLa nuclear extracts). It inhibits growth of U937 and HUT cancer cells (IC50s = <330 nM).

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Suppliers and manufacturers

ATK CHEMICAL COMPANY LIMITED
Zhejiang J&C Biological Technology Co.,Limited
InvivoChem
TargetMol Chemicals Inc.
ShenZhen Trendseen Biological Technology Co.,Ltd.
Wuhan Topule Biopharmaceutical Co., Ltd
Aladdin Scientific
Amadis Chemical Company Limited Chuzhou KeMail Chemical Technology Co., Ltd Shanghai Han-Xiang Chemical Co., Ltd.