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1,2-DI[CIS-9-OCTADECENOYL]-SN-GLYCERO-3-PHOSPHATE SODIUM SALT

1,2-DI[CIS-9-OCTADECENOYL]-SN-GLYCERO-3-PHOSPHATE SODIUM SALT Structure
  • ₹3907.83 - ₹33828.13
  • Product name: 1,2-DI[CIS-9-OCTADECENOYL]-SN-GLYCERO-3-PHOSPHATE SODIUM SALT
  • CAS: 108392-02-5
  • MF: C39H74NaO8P
  • MW: 724.98
  • EINECS:
  • MDL Number:MFCD00674303
  • Synonyms:PHOSPHATIDIC ACID, DIOLEOYL, SODIUM SALT;1,2-DIOLEYOYL-SN-GLYCERO-3-PHOSPHATE NA;1,2-DI[CIS-9-OCTADECENOYL]-SN-GLYCERO-3-PHOSPHATE SODIUM SALT;L-ALPHA-PHOSPHATIDIC ACID, DIOLEOYL SODIUM SALT;L-A-phosphatidic acid dioleoyl sodium;1,2-di(cis-9-octadecenoyl)-sn-glycerol 3-phosphate sodium salt;l-α-phosphatidic acid, dioleoyl sodium salt;1,2-Dioleoyl-sn-glycero-3-phosphoric acid monosodium salt
3 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 5MG
  • 10MG
  • 100MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberP2767
  • Product description1,2-Di(cis-9-octadecenoyl)-sn-glycerol 3-phosphate sodium salt ≥99% (GC), ≥97% (TLC)
  • Packaging5MG
  • Price₹3907.83
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberP2767
  • Product description1,2-Di(cis-9-octadecenoyl)-sn-glycerol 3-phosphate sodium salt ≥99% (GC), ≥97% (TLC)
  • Packaging10MG
  • Price₹10911.6
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberP2767
  • Product description1,2-Di(cis-9-octadecenoyl)-sn-glycerol 3-phosphate sodium salt ≥99% (GC), ≥97% (TLC)
  • Packaging100MG
  • Price₹33828.13
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) P2767 1,2-Di(cis-9-octadecenoyl)-sn-glycerol 3-phosphate sodium salt ≥99% (GC), ≥97% (TLC) 5MG ₹3907.83 2022-06-14 Buy
Sigma-Aldrich(India) P2767 1,2-Di(cis-9-octadecenoyl)-sn-glycerol 3-phosphate sodium salt ≥99% (GC), ≥97% (TLC) 10MG ₹10911.6 2022-06-14 Buy
Sigma-Aldrich(India) P2767 1,2-Di(cis-9-octadecenoyl)-sn-glycerol 3-phosphate sodium salt ≥99% (GC), ≥97% (TLC) 100MG ₹33828.13 2022-06-14 Buy

Properties

storage temp. :−20°C
solubility :Methanol: soluble
form :White powder.
color :Colorless to light yellow

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H331 Toxic if inhaled Acute toxicity,inhalation Category 3 Danger GHS hazard pictograms P261, P271, P304+P340, P311, P321,P403+P233, P405, P501
H336 May cause drowsiness or dizziness Specific target organ toxicity,single exposure; Narcotic effects Category 3 Warning P261, P271, P304+P340, P312,P403+P233, P405, P501
H351 Suspected of causing cancer Carcinogenicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
H372 Causes damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 1 Danger GHS hazard pictograms P260, P264, P270, P314, P501
H412 Harmful to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 3 P273, P501
Precautionary statements:
P201 Obtain special instructions before use.
P273 Avoid release to the environment.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

Phosphatidic Acid, Dioleoyl has been shown to activate PKC α, ε, or ζ isotypes in the cytosol of COS cells. This compound not only stimulates PKC-ζ-mediated phosphorylation of distinctive substrates, but additionally causes an upward shift in electrophoretic mobility of PKC &zeta. Furthermore, experiments have reported Phosphatidic Acid to be generated by hydrolysis of phosphatidylcholine, via phospholipase D (PLD). Mechanistic studies suggest activation of PLD by insulin and consequential generation of Phosphatidic Acid which then induces Raf-1 translocation to cell membranes. Raf-1 is an essential component to the mitogen-activated protein kinase cascade, and once it has crossed over to the plasma membrane, other factors may activate it through phosphorylation.

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