Prostratin, PKC activator
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- ₹12773.5 - ₹51765.15
- Product name: Prostratin, PKC activator
- CAS: 60857-08-1
- MF: C22H30O6
- MW: 390.47
- EINECS:
- MDL Number:MFCD00674138
- Synonyms:SA 101A;Prostatin >99%;12-Deoxyphorbol 13-Acetate, dPAc;(1aR,1bS,4aR,7aS,7bR,8R,9aS)-9a-(Acetyloxy)-1,1a,1b,4,4a,7a,7b,8,9,9a -decahydro-4a,7b-dihydroxy-3-(hydroxyMethyl)-1,1,6,8-tetraMethyl-;13-O-Acetyl-12-deoxyphorbol;PROSTRATIN;(1aR,1bS,4aR,7aS,7bR,8R,9aS)-9a-(Acetyloxy)-1,1a,1b,4,4a,7a,7b,8,9,9a -decahydro-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl- 5H-cyclopropa[3,4]benz[1,2-e]azulen-5-one;13-O-Acetylphorbol
2 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 1MG
- 5MG
- ManufacturerSigma-Aldrich(India)
- Product numberP0077
- Product descriptionProstratin ≥98% (HPLC)
- Packaging1MG
- Price₹12773.5
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberP0077
- Product descriptionProstratin ≥98% (HPLC)
- Packaging5MG
- Price₹51765.15
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | P0077 | Prostratin ≥98% (HPLC) | 1MG | ₹12773.5 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | P0077 | Prostratin ≥98% (HPLC) | 5MG | ₹51765.15 | 2022-06-14 | Buy |
Properties
Melting point :216-219℃
Boiling point :550.5±50.0 °C(Predicted)
Density :1.31
storage temp. :-20°C
solubility :Soluble in DMSO at 30mg/ml
form :white powder
pka :11.40±0.70(Predicted)
color :Off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
Boiling point :550.5±50.0 °C(Predicted)
Density :1.31
storage temp. :-20°C
solubility :Soluble in DMSO at 30mg/ml
form :white powder
pka :11.40±0.70(Predicted)
color :Off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
Safety Information
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Description
Activation of latent reservoirs of HIV-infected cells is a treatment strategy designed to reduce viral load and eliminate the perpetuation of retroviral infection. Prostratin is a non-tumor promoting phorbol ester that potently induces HIV-1 reactivation in latent reservoirs of infected Jurkat-LAT-GFP cells with an IC50 value of ~0.5 μM. Originally, prostratin was isolated from plant sources including P. prostrata, E. cornigera, and H. nutans. The effects of prostratin are mediated through activation of NF-κB via protein kinase C and by downregulation of HIV-1 receptor CD4 expression and its co-receptors CXCR4 and CCR5.Related product price
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