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ChemicalBook > Product Catalogue >Chemical Reagents >Organic reagents >Esters >Carboxylic Acid Esters >PHORBOL 12-MYRISTATE 13-ACETATE

PHORBOL 12-MYRISTATE 13-ACETATE

PHORBOL 12-MYRISTATE 13-ACETATE Structure
  • ₹7015 - ₹127475.2
  • Product name: PHORBOL 12-MYRISTATE 13-ACETATE
  • CAS: 16561-29-8
  • MF: C36H56O8
  • MW: 616.83
  • EINECS:605-413-5
  • MDL Number:MFCD00036736
  • Synonyms:13-o-acetylphorbol12-myristate ;4)benz(1,2-e)azulen-5-one9a-acetate,(+)-ethyl-5h-cyclopropa( ;5h-cyclopropa(3,4)benz(1,2-e)azulen-5-one,1,1a-beta,1b-alpha,4,4a,7a-beta,7b, ;4BETA-PHORBOL 12-MYRISTATE 13-ACETATE;4BETA,9ALPHA,12BETA,13ALPHA,20-PENTA-HYDROXYTIGLIA-1,6-DIEN-3-ONE 12BETA-MYRISTATE 13-ACETATE;4ALPHA,9ALPHA,12BETA,13ALPHA,20-PENTAHYDROXYTIGLIA-1,6-DIEN-3-ONE 12BETA-MYRISTATE 13-ACETATE;(1AR,1BS,4AR,7AS,7BS,8R,9R,9AS)-9A-(ACETYLOXY)-1A,1B,4,4A,5,7A,7B,8,9,9A-DECAHYDRO-4A,7B-DIHYDROXY-3-(HYDROXYMETHYL)-1,1,6,8-TETRAMETHYL-5-OXO-1H-CYCLOPROPA[3,4]BENZ[1,2-E]AZULEN-9-YL TETRADECANOATE;12-TETRADECANOYL PHORBOL 13-ACETATE
19 prices
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Brand

  • ALFA India
  • Sigma-Aldrich(India)

Package

  • 1mg
  • 2MG
  • 5mg
  • 10mg
  • 25mg
  • ManufacturerALFA India
  • Product numberALF-J63916-MCR
  • Product descriptionPhorbol 12-myristate 13-acetate, 99+%
  • Packaging1mg
  • Price₹7015
  • Updated2022-05-26
  • Buy
  • ManufacturerALFA India
  • Product numberALF-J63916-LB0
  • Product descriptionPhorbol 12-myristate 13-acetate, 99+%
  • Packaging5mg
  • Price₹7417
  • Updated2022-05-26
  • Buy
  • ManufacturerALFA India
  • Product numberALF-J63916-MB
  • Product descriptionPhorbol 12-myristate 13-acetate, 99+%
  • Packaging25mg
  • Price₹25105
  • Updated2022-05-26
  • Buy
  • ManufacturerALFA India
  • Product numberALF-J63916-MA
  • Product descriptionPhorbol 12-myristate 13-acetate, 99+%
  • Packaging10mg
  • Price₹40703
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number524400
  • Product descriptionPhorbol-12-myristate-13-acetate - CAS 16561-29-8 - Calbiochem Phorbol-12-myristate-13-acetate, CAS 16561-29-8, is the most common phorbol ester. Activates PKC at nanomolar concentrations.
  • Packaging1MG
  • Price₹10790.01
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number79346
  • Product descriptionPhorbol 12-myristate 13-acetate synthetic, ≥98.0% (TLC)
  • Packaging1MG
  • Price₹11485.33
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberP1585
  • Product descriptionPMA for use in molecular biology applications, ≥99% (HPLC)
  • Packaging1MG
  • Price₹12546.18
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberP8139
  • Product descriptionPhorbol 12-myristate 13-acetate ≥99% (TLC), film or powder
  • Packaging1MG
  • Price₹12654.43
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number5.00582
  • Product descriptionInSolution Phorbol-12-myristate-13-acetate - CAS 16561-29-8 - Calbiochem
  • Packaging2MG
  • Price₹12940
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number524400
  • Product descriptionPhorbol-12-myristate-13-acetate - CAS 16561-29-8 - Calbiochem Phorbol-12-myristate-13-acetate, CAS 16561-29-8, is the most common phorbol ester. Activates PKC at nanomolar concentrations.
  • Packaging5MG
  • Price₹19140
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number524400
  • Product descriptionPhorbol-12-myristate-13-acetate - CAS 16561-29-8 - Calbiochem Phorbol-12-myristate-13-acetate, CAS 16561-29-8, is the most common phorbol ester. Activates PKC at nanomolar concentrations.
  • Packaging25MG
  • Price₹87320
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberP1585
  • Product descriptionPMA for use in molecular biology applications, ≥99% (HPLC)
  • Packaging25MG
  • Price₹103151.43
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberP8139
  • Product descriptionPhorbol 12-myristate 13-acetate ≥99% (TLC), film or powder
  • Packaging25MG
  • Price₹127475.2
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number79346
  • Product descriptionPhorbol 12-myristate 13-acetate synthetic, ≥98.0% (TLC)
  • Packaging5MG
  • Price₹22797.45
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberP8139
  • Product descriptionPhorbol 12-myristate 13-acetate ≥99% (TLC), film or powder
  • Packaging5MG
  • Price₹32345.1
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number524400
  • Product descriptionPhorbol-12-myristate-13-acetate - CAS 16561-29-8 - Calbiochem Phorbol-12-myristate-13-acetate, CAS 16561-29-8, is the most common phorbol ester. Activates PKC at nanomolar concentrations.
  • Packaging10MG
  • Price₹38970
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
ALFA India ALF-J63916-MCR Phorbol 12-myristate 13-acetate, 99+% 1mg ₹7015 2022-05-26 Buy
ALFA India ALF-J63916-LB0 Phorbol 12-myristate 13-acetate, 99+% 5mg ₹7417 2022-05-26 Buy
ALFA India ALF-J63916-MB Phorbol 12-myristate 13-acetate, 99+% 25mg ₹25105 2022-05-26 Buy
ALFA India ALF-J63916-MA Phorbol 12-myristate 13-acetate, 99+% 10mg ₹40703 2022-05-26 Buy
Sigma-Aldrich(India) 524400 Phorbol-12-myristate-13-acetate - CAS 16561-29-8 - Calbiochem Phorbol-12-myristate-13-acetate, CAS 16561-29-8, is the most common phorbol ester. Activates PKC at nanomolar concentrations. 1MG ₹10790.01 2022-06-14 Buy
Sigma-Aldrich(India) 79346 Phorbol 12-myristate 13-acetate synthetic, ≥98.0% (TLC) 1MG ₹11485.33 2022-06-14 Buy
Sigma-Aldrich(India) P1585 PMA for use in molecular biology applications, ≥99% (HPLC) 1MG ₹12546.18 2022-06-14 Buy
Sigma-Aldrich(India) P8139 Phorbol 12-myristate 13-acetate ≥99% (TLC), film or powder 1MG ₹12654.43 2022-06-14 Buy
Sigma-Aldrich(India) 5.00582 InSolution Phorbol-12-myristate-13-acetate - CAS 16561-29-8 - Calbiochem 2MG ₹12940 2022-06-14 Buy
Sigma-Aldrich(India) 524400 Phorbol-12-myristate-13-acetate - CAS 16561-29-8 - Calbiochem Phorbol-12-myristate-13-acetate, CAS 16561-29-8, is the most common phorbol ester. Activates PKC at nanomolar concentrations. 5MG ₹19140 2022-06-14 Buy
Sigma-Aldrich(India) 524400 Phorbol-12-myristate-13-acetate - CAS 16561-29-8 - Calbiochem Phorbol-12-myristate-13-acetate, CAS 16561-29-8, is the most common phorbol ester. Activates PKC at nanomolar concentrations. 25MG ₹87320 2022-06-14 Buy
Sigma-Aldrich(India) P1585 PMA for use in molecular biology applications, ≥99% (HPLC) 25MG ₹103151.43 2022-06-14 Buy
Sigma-Aldrich(India) P8139 Phorbol 12-myristate 13-acetate ≥99% (TLC), film or powder 25MG ₹127475.2 2022-06-14 Buy
Sigma-Aldrich(India) 79346 Phorbol 12-myristate 13-acetate synthetic, ≥98.0% (TLC) 5MG ₹22797.45 2022-06-14 Buy
Sigma-Aldrich(India) P8139 Phorbol 12-myristate 13-acetate ≥99% (TLC), film or powder 5MG ₹32345.1 2022-06-14 Buy
Sigma-Aldrich(India) 524400 Phorbol-12-myristate-13-acetate - CAS 16561-29-8 - Calbiochem Phorbol-12-myristate-13-acetate, CAS 16561-29-8, is the most common phorbol ester. Activates PKC at nanomolar concentrations. 10MG ₹38970 2022-06-14 Buy

Properties

Melting point :65-79oC
Boiling point :571.87°C (rough estimate)
Density :1.17±0.1 g/cm3 (20 ºC 760 Torr)
refractive index :1.4900 (estimate)
storage temp. :-20°C
solubility :DMSO: DMSO solutions can be stored dark at −20°C for at least six months.soluble
pka :11.19±0.70(Predicted)
form :Fine Crystalline Powder
color :Off-white to light yellow
Water Solubility :Very soluble in methanol, soluble in DMSO, chloroform, ethanol or acetone, ether, ethyl acetate, DMF or acetonitrile. Insoluble in water.
Sensitive :Light Sensitive
BRN :2407201
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.
InChIKey :PHEDXBVPIONUQT-RGYGYFBISA-N
CAS DataBase Reference :16561-29-8(CAS DataBase Reference)
EPA Substance Registry System :12-O-Tetradecanoylphorbol 13-acetate (16561-29-8)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H314 Causes severe skin burns and eye damage Skin corrosion/irritation Category 1A, B, C Danger GHS hazard pictograms P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled Sensitisation, respiratory Category 1 Danger GHS hazard pictograms P261, P285, P304+P341, P342+P311,P501
H351 Suspected of causing cancer Carcinogenicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
Precautionary statements:
P202 Do not handle until all safety precautions have been read and understood.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

PMA activates Ca2+- ATPase and potentiates forskolin-induced cAMP formation. It has been shown to inhibit apoptosis induced by the Fas antigen, but PMA induces apoptosis in HL-60 promyelocytic leukemia cells.

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