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(1R,2S,5R)-5-Methyl-2-(1-methylethyl)cyclohexyl dihydroxy-acetate

(1R,2S,5R)-5-Methyl-2-(1-methylethyl)cyclohexyl dihydroxy-acetate Structure
  • ₹4400
  • Product name: (1R,2S,5R)-5-Methyl-2-(1-methylethyl)cyclohexyl dihydroxy-acetate
  • CAS: 111969-64-3
  • MF: C12H22O4
  • MW: 230.3
  • EINECS:416-810-6
  • MDL Number:MFCD00154508
  • Synonyms:(1S)-(+)-MENTHYL GLYOXYLATE HYDRATE;Glyoxylic acid (1S)-menthyl ester hydrate;L)-Menthyl glyoxylate monohydrate;(S)-(+)-MENTHYL GLYOXYLATE HYDRATE;(1R,2S,5R)-5-Methyl-2-(1-methylethyl)cyclohexyl dihydroxy-acetate;2,2-Dihydroxyacetic acid (-)-menthyl ester;L-Menthyl glyoxylate hydrate;L-MGH
Price1 Properties Safety Information Description
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Brand

  • TCI Chemicals (India)

Package

  • 25G
  • ManufacturerTCI Chemicals (India)
  • Product numberI0790
  • Product description(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl 2,2-Dihydroxyacetate min. 98.0 %
  • Packaging25G
  • Price₹4400
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) I0790 (1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl 2,2-Dihydroxyacetate min. 98.0 % 25G ₹4400 2022-05-26 Buy

Properties

Melting point :76-78°C
Boiling point :320°C
Density :1.09
Flash point :113°C
storage temp. :Sealed in dry,Room Temperature
solubility :soluble in Methanol
form :powder to crystal
pka :10.79±0.41(Predicted)
color :White to Almost white
Water Solubility :400g/L
Sensitive :Air Sensitive
BRN :4905777
CAS DataBase Reference :111969-64-3(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger GHS hazard pictograms P280, P305+P351+P338, P310
H373 May cause damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 2 Warning P260, P314, P501
H411 Toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 2
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P314 Get medical advice/attention if you feel unwell.

Description

L-Menthyl 2,2-Dihydroxyacetate is used as a reagent in the synthesis of Lamivudine (L172500); a potent nucleoside reverse transcriptase inhibitor used for the treatment of chronic hepatitis B. L-Menthyl 2,2-Dihydroxyacetate is also used as a reagent in the synthesis of 4-acetoxy-3-hydroxyethylazetidin-2-one, a key intermediate for the preparation of penem and carbapenem antibiotics.

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(1R,2S,5R)-Menthyl-(2R,5S)-5-(4-amino-2-oxo-2H-pyrimidin-1-yl)-[1,3]oxathiolane-2-carboxylic acid (2R,5R)-5-Hydroxy-1,3-oxathiolane-2-carboxylic acid (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester L-MENTHYL ACETATE 111969-64-3 Glyoxylic acid monohydrate Cyclohexanol Glyoxylic acid

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Suppliers and manufacturers

Styrax Pharma Pvt Ltd Orch Laboratories India Pvt Ltd TCI Chemicals (India) Pvt. Ltd. Chephis Corporation Akshaya Laboratories Pvt. Ltd Clearsynth Labs S. Amit Speciality Chemicals Pvt. Ltd. Auctus Pharma Limited Orch Laboratories India Pvt Ltd. Styrax Pharma Private Ltd.