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10,10-BIS(4-PYRIDINYLMETHYL)-9(10H)-ANTHRACENONE DIHYDROCHLORIDE

10,10-BIS(4-PYRIDINYLMETHYL)-9(10H)-ANTHRACENONE DIHYDROCHLORIDE Structure
  • ₹17612.28 - ₹74833.23
  • Product name: 10,10-BIS(4-PYRIDINYLMETHYL)-9(10H)-ANTHRACENONE DIHYDROCHLORIDE
  • CAS: 122955-42-4
  • MF: C26H20N2O
  • MW: 376.45
  • EINECS:
  • MDL Number:MFCD05662331
  • Synonyms:10,10-BIS(4-PYRIDINYLMETHYL)-9(10H)-ANTHRACENONE DIHYDROCHLORIDE;XE9912HCl;XE 991;XE 991 DIHYDROCHLORIDE;10-bis(4-Pyridinylmethyl)-9(10H)-anthracenone dihydrochloride;9(10H)-Anthracenone, 10,10-bis(4-pyridinylmethyl)-;10,10-Bis(pyridin-4-ylmethyl)anthracen-9(10H)-one
Price2 Properties Safety Information Description
2 prices
Selected condition：

Brand

  • Sigma-Aldrich(India)

Package

  • 10MG
  • 50MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberX2254
  • Product descriptionXE-991 ≥98% (HPLC)
  • Packaging10MG
  • Price₹17612.28
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberX2254
  • Product descriptionXE-991 ≥98% (HPLC)
  • Packaging50MG
  • Price₹74833.23
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) X2254 XE-991 ≥98% (HPLC) 10MG ₹17612.28 2022-06-14 Buy
Sigma-Aldrich(India) X2254 XE-991 ≥98% (HPLC) 50MG ₹74833.23 2022-06-14 Buy

Properties

Melting point :231-232 °C
Boiling point :585.0±38.0 °C(Predicted)
Density :1.238±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >20mg/mL
form :solid
pka :6.08±0.10(Predicted)
color :white to beige
Water Solubility :Soluble in water (100mM)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

XE 991 dihydrochloride is a potent and selective blocker of KCNQ voltage-gated potassium channels. Blocks KCNQ2+3/M-currents (IC50 = 0.6-0.98 μM) and KCNQ1 homomeric channels (IC50 = 0.75 μM) but is less potent against KCNQ1/minK channels (IC50 = 11.1 μM).

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