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ChemicalBook > Product Catalogue >Biochemical Engineering >Amino Acids and Derivatives >FMOC-amino acid >N-Fmoc-8-Aminooctanoic acid

N-Fmoc-8-Aminooctanoic acid

N-Fmoc-8-Aminooctanoic acid Structure
  • ₹7620.8 - ₹24039
  • Product name: N-Fmoc-8-Aminooctanoic acid
  • CAS: 126631-93-4
  • MF: C23H27NO4
  • MW: 381.46
  • EINECS:
  • MDL Number:MFCD00235890
  • Synonyms:N-FMOC-8-AMINOOCTANOIC ACID;N-(9-FLUORENYLMETHYLOXYCARBONYL)-8-AMINO-OCTANOIC ACID;N-(9-FLUORENYLMETHOXYCARBONYL)-8-AMINOCAPRYLIC ACID;N-(9-FLUORENYLMETHOXYCARBONYL)-8-AMINOOCTANOIC ACID;N-ALPHA-FMOC-8-AMINOOCTANOIC ACID;RARECHEM EM WB 0026;FMOC-NH-(CH2)7-COOH;FMOC-AOC(8)-OH
2 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)
  • ottokemi

Package

  • 500MG
  • ManufacturerSigma-Aldrich(India)
  • Product number47998
  • Product descriptionFmoc-8-Aoc-OH ≥98.0% (HPLC)
  • Packaging500MG
  • Price₹7620.8
  • Updated2022-06-14
  • Buy
  • Manufacturerottokemi
  • Product number F 4813
  • Product descriptionFmoc-8-Aoc-OH, ≥98% (HPLC)
  • Packaging500mg
  • Price₹24039
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) 47998 Fmoc-8-Aoc-OH ≥98.0% (HPLC) 500MG ₹7620.8 2022-06-14 Buy
ottokemi F 4813 Fmoc-8-Aoc-OH, ≥98% (HPLC) 500mg ₹24039 2022-05-26 Buy

Properties

Melting point :118-119 °C(Solv: ethyl acetate (141-78-6); ligroine (8032-32-4))
Boiling point :597.7±33.0 °C(Predicted)
Density :1.174±0.06 g/cm3(Predicted)
storage temp. :2-8°C
pka :4.77±0.10(Predicted)
form :Powder
color :White
BRN :8286497
CAS DataBase Reference :126631-93-4(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

N-Fmoc-8-aminooctanoic acid can be used as a PROTAC linker in the synthesis of PROTACs. N-Fmoc-8-aminooctanoic acid is an alkane chian with terminal Fmoc-protected amine and carboxylic acid groups. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

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