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12(S)-HETE

12(S)-HETE Structure
  • ₹24006.5
  • Product name: 12(S)-HETE
  • CAS: 54397-83-0
  • MF: C20H32O3
  • MW: 320.47
  • EINECS:200-578-6
  • MDL Number:MFCD00036916
  • Synonyms:12(S)-HYDROXY-(5Z,8Z,10E,14Z)-EICOSATETRAENOIC ACID;12(S)-HETE;12(S)-HYDROXYEICOSA-5Z,8Z,10E,14Z-TETRAENOIC ACID;12(S)-HETE Lipid Maps MS Standard;[S-(E,Z,Z,Z)]-12-Hydroxy-5,8,10,14-eicosatetraenoic Acid;12-L-Hydroxy-5,8,10,14-eicosatetraenoic Acid;(12S,5Z,8Z,10E,14Z)-12-Hydroxyeicosatetraenoic acid;12(S)-hydroxy-(5Z,8Z,10E,14Z)-*eicosatetraenoic A
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Brand

  • Sigma-Aldrich(India)

Package

  • 10μG
  • ManufacturerSigma-Aldrich(India)
  • Product numberH7768
  • Product description12(S)-Hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoic acid ~100?μg/mL in ethanol, ≥95% (HPLC)
  • Packaging10μG
  • Price₹24006.5
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) H7768 12(S)-Hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoic acid ~100?μg/mL in ethanol, ≥95% (HPLC) 10μG ₹24006.5 2022-06-14 Buy

Properties

Boiling point :487.7±45.0 °C(Predicted)
Density :0.984±0.06 g/cm3(Predicted)
Flash point :14 °C
storage temp. :-20°C
solubility :0.1 M Na2CO3: 2 mg/ml; DMF: Miscible; DMSO: Miscible; Ethanol: Miscible; PBS pH 7.2: 0.8 mg/ml
form :Liquid.
pka :4.75±0.10(Predicted)
color :Colorless to light yellow
BRN :2656104

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger GHS hazard pictograms P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

12(S)-HETE is the predominant lipoxygenase product of mammalian platelets. It enhances tumor cell adhesion to endothelial cells, fibronectin, and the subendothelial matrix at 0.1 μM.

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