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5,8,11-EICOSATRIYNOIC ACID

5,8,11-EICOSATRIYNOIC ACID Structure
  • ₹0
  • Product name: 5,8,11-EICOSATRIYNOIC ACID
  • CAS: 13488-22-7
  • MF: C20H28O2
  • MW: 300.44
  • EINECS:200-533-0
  • MDL Number:MFCD00077343
  • Synonyms:5,8,11-Icosatriynoic acid;5,8,11-EICOSATRIYNOIC ACID;OWYNLPMPYBYKJP-UHFFFAOYSA-N;Icosa-5,8,11-triynoic acid;5,8,11-EICOSATRIYNOIC ACID Basic information;5,8,11-EICOSATRIYNOIC ACID ISO 9001:2015 REACH;EICOSATRIYNOIC ACID;ETI
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Properties

Melting point :70.5-71.5 °C
Boiling point :473.8±40.0 °C(Predicted)
Density :0.990±0.06 g/cm3(Predicted)
storage temp. :−20°C
solubility :Chloroform (Slightly), Methanol (Slightly)
form :Off-white solid.
pka :4.61±0.10(Predicted)
color :Pale Yellow to Pale Beige
Stability :Light Sensitive

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

5,8,11-ETI is a nonselective inhibitor of lipoxygenases. It inhibits 12-LO in human platelets with an ID50 value of 24 μM. 5,8,11-ETI also inhibits A23187 and L-cysteine induced LTC4 biosynthesis in mouse mastocytoma cells with an ID50 value of 5 μM. At higher concentrations, 5,8,11-ETI also inhibits cyclooxygenases (ID50 = 340 μM).

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