H-TYR-LEU-TYR-GLN-TRP-LEU-GLY-ALA-PRO-VAL-PRO-TYR-PRO-ASP-PRO-LEU-GLA-PRO-ARG-ARG-GLA-VAL-CYS-GLA-LEU-ASN-PRO-ASP-CYS-ASP-GLU-LEU-ALA-ASP-HIS-ILE-GLY-PHE-GLN-GLU-ALA-TYR-ARG-ARG-PHE-TYR-GLY-PRO-VAL-OH
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- ₹81901.95 - ₹135842.93
- Product name: H-TYR-LEU-TYR-GLN-TRP-LEU-GLY-ALA-PRO-VAL-PRO-TYR-PRO-ASP-PRO-LEU-GLA-PRO-ARG-ARG-GLA-VAL-CYS-GLA-LEU-ASN-PRO-ASP-CYS-ASP-GLU-LEU-ALA-ASP-HIS-ILE-GLY-PHE-GLN-GLU-ALA-TYR-ARG-ARG-PHE-TYR-GLY-PRO-VAL-OH
- CAS: 136461-80-8
- MF: C269H381N67O82S2
- MW: 5929.43
- EINECS:
- MDL Number:MFCD00147801
- Synonyms:OSTEOCALCIN (HUMAN, GLA17,21,24);OSTEOCALCIN (1-49) (HUMAN);TYR-LEU-TYR-GLN-TRP-LEU-GLY-ALA-PRO-VAL-PRO-TYR-PRO-ASP-PRO-LEU-GLA-PRO-ARG-ARG-GLA-VAL-CYS-GLA-LEU-ASN-PRO-ASP-CYS-ASP-GLU-LEU-ALA-ASP-HIS-ILE-GLY-PHE-GLN-GLU-ALA-TYR-ARG-ARG-PHE-TYR-GLY-PRO-VAL;YLYQWLGAPVPYPDPL-GLA-PRR-GLA-VC-GLA-LNPDCDELADHIGFQEAYRRFYGPV;H-TYR-LEU-TYR-GLN-TRP-LEU-GLY-ALA-PRO-VAL-PRO-TYR-PRO-ASP-PRO-LEU-GLA-PRO-ARG-ARG-GLA-VAL-CYS-GLA-LEU-ASN-PRO-ASP-CYS-ASP-GLU-LEU-ALA-ASP-HIS-ILE-GLY-PHE-GLN-GLU-ALA-TYR-ARG-ARG-PHE-TYR-GLY-PRO-VAL-OH;[GLA17,21,24]-OSTEOCALCIN (1-49);GLA17,21,24-OSTEOCALCIN (HUMAN);BONE GLA PROTEIN (HUMAN)
2 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 1MG
- 500μG
- ManufacturerSigma-Aldrich(India)
- Product numberO5761
- Product descriptionOsteocalcin fragment 1-49 Human ≥94% (HPLC), solid
- Packaging500μG
- Price₹81901.95
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberO5761
- Product descriptionOsteocalcin fragment 1-49 Human ≥94% (HPLC), solid
- Packaging1MG
- Price₹135842.93
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | O5761 | Osteocalcin fragment 1-49 Human ≥94% (HPLC), solid | 500μG | ₹81901.95 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | O5761 | Osteocalcin fragment 1-49 Human ≥94% (HPLC), solid | 1MG | ₹135842.93 | 2022-06-14 | Buy |
Properties
storage temp. :-20°C
solubility :Formic Acid: 1 mg/ml
form :solid
solubility :Formic Acid: 1 mg/ml
form :solid
Safety Information
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Description
Osteocalcin (1-49) is a non-collagenous peptide that is secreted by osteoblasts and odontoblasts and comprises 1-2% of the total protein in bone. Secretion of osteocalcin (1-49) is stimulated by 1,25-dihydroxy vitamin D and plasma levels increase in diseases that induce dysregulated bone turnover such as osteoporosis, Paget''s disease, and primary hyperparathyroidism. Osteocalcin (1-49) is positively correlated with insulin sensitivity and negatively correlated with high blood glucose levels in women. In vitro, osteocalcin induces chemotaxis of MDA-MB-231 breast cancer cells, human peripheral blood monocytes, and rat osteosarcoma cells with osteoblast-like characteristics. It is also expressed by vascular smooth muscle cells (VSMCs) displaying an osteoblast-like phenotype and has been positively associated with calcification of aortic tissue and heart valves in humans.Related product price
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