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(2R,3R)-3,5,7-Trihydroxy-2-[(2S,3S)-2-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-2,3-dihydrobenzo[1,4]dioxin-6-yl]-4-chromanone

(2R,3R)-3,5,7-Trihydroxy-2-[(2S,3S)-2-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-2,3-dihydrobenzo[1,4]dioxin-6-yl]-4-chromanone Structure
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Brand

  • Sigma-Aldrich(India)

Package

  • 5MG
  • ManufacturerSigma-Aldrich(India)
  • Product number95684
  • Product descriptionIsosilybin B analytical standard
  • Packaging5MG
  • Price₹79617.88
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) 95684 Isosilybin B analytical standard 5MG ₹79617.88 2022-06-14 Buy

Properties

Melting point :194-196 °C(Solv: methanol (67-56-1))
Boiling point :793.0±60.0 °C(Predicted)
Density :1.527±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Soluble in DMSO
form :Solid
pka :7.39±0.60(Predicted)
color :White to off-white

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P501 Dispose of contents/container to..…

Description

Isosilybin B is one of the flavonolignans extracted from the seeds of milk thistle. Isosilybin B was the most consistently potent suppressor of cell growth. Isosilybin A (I901002) and isosilybin B were also the most effective suppressors of prostate-?specific antigen secretion by androgen-?dependent LNCaP cells.

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