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ChemicalBook > Product Catalogue >Pharmaceutical intermediates >Heterocyclic compound >Pyrimidines >Thio pyrimidine >4,6-DICHLORO-5-NITRO-2-PROPYLTHIOPYRIMIDINE

4,6-DICHLORO-5-NITRO-2-PROPYLTHIOPYRIMIDINE

4,6-DICHLORO-5-NITRO-2-PROPYLTHIOPYRIMIDINE Structure
  • ₹0
  • Product name: 4,6-DICHLORO-5-NITRO-2-PROPYLTHIOPYRIMIDINE
  • CAS: 145783-14-8
  • MF: C7H7Cl2N3O2S
  • MW: 268.12
  • EINECS:700-475-0
  • MDL Number:MFCD10698669
  • Synonyms:4,6-DICHLORO-5-NITRO-2-PROPYLTHIOPYRIMIDINE;PyriMidine, 4,6-dichloro-5-nitro-2-(propylthio)-;4,6-dichloro-5-nitro-2-(propylsulfanyl)pyriMidine;4,6-dichloro-5-nitro-2-(propylsulfanyl)pyriMidine 4,6-dichloro-5-nitro-2-(propylsulfanyl)pyriMidine;4,6-DICHLORO-5-NITRO-2-PROPYLTHIOPYRIMIDI;4,6-Dichloro-5-nitro-2-(propythio)pyrimidine;4,6-Dichloro-5-nitro-2-propylthiopyridine;EOS-61674
Properties Safety Information Description
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Boiling point :377.8±37.0 °C(Predicted)
Density :1.54±0.1 g/cm3(Predicted)
vapor pressure :0.005Pa at 25℃
storage temp. :Inert atmosphere,Room Temperature
solubility :Chloroform (Sparingly), DMSO (Sparingly), Ethyl Acetate (Slightly)
pka :-8.48±0.50(Predicted)
form :Oil
color :Colourless to Dark Yellow
Stability :Unstable in DMSO Solution
LogP :2.6 at 25℃ and pH7.3
Surface tension :70.5-71.7mN/m at 9.1mg/L and 25℃

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H311 Toxic in contact with skin Acute toxicity,dermal Category 3 Danger GHS hazard pictograms P280, P302+P352, P312, P322, P361,P363, P405, P501
H314 Causes severe skin burns and eye damage Skin corrosion/irritation Category 1A, B, C Danger GHS hazard pictograms P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H373 May cause damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 2 Warning P260, P314, P501
H410 Very toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 1 Warning GHS hazard pictograms P273, P391, P501
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P272 Contaminated work clothing should not be allowed out of the workplace.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P301+P330+P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310 Immediately call a POISON CENTER or doctor/physician.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P314 Get medical advice/attention if you feel unwell.
P321 Specific treatment (see … on this label).
P322 Specific measures (see …on this label).
P330 Rinse mouth.
P333+P313 IF SKIN irritation or rash occurs: Get medical advice/attention.
P361 Remove/Take off immediately all contaminated clothing.
P363 Wash contaminated clothing before reuse.
P391 Collect spillage. Hazardous to the aquatic environment
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

4,6-Dichloro-5-nitro-2-(propylthio)pyrimidine is used as a reactnat in the synthesis of carba-nucleosides as potent antagonists of ADP purinergic receptor P2Y12 on human platelets.

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