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ChemicalBook > Product Catalogue >API >Blood System Drugs >Anticoagulant and Antiplatelet Drugs >TICAGRELOR

TICAGRELOR

TICAGRELOR Structure
  • ₹6016.2 - ₹12154.5
  • Product name: TICAGRELOR
  • CAS: 274693-27-5
  • MF: C23H28F2N6O4S
  • MW: 522.57
  • EINECS:619-540-9
  • MDL Number:MFCD09954148
  • Synonyms:1,2-Cyclopentanediol, 3-[7-[[(1R,2S)-2-(3,4-difluorophenyl)cyclopropyl]amino]-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)-, (1S,2S,3R,5S)-;Ticagrelor, >=98%;Ticagrelo;Ticarelor;Brilique;(1S,2S,3R,5S)-3-[7-[[(1R,2S)-2-(3,4-difluorophenyl)cyclopropyl]amino]-5-propylsulfanyltriazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)cyclopentane-1,2-diol;TICAGRELOR;(1S,2S,3R,5S)-3-[7-[[(1R,2S)-2-(3,4-Difluorophenyl)cyclopropyl]amino]-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)-1,2-cyclopentanediol
2 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 10MG
  • 50MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML2482
  • Product descriptionTicagrelor ≥98% (HPLC)
  • Packaging10MG
  • Price₹6016.2
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML2482
  • Product descriptionTicagrelor ≥98% (HPLC)
  • Packaging50MG
  • Price₹12154.5
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) SML2482 Ticagrelor ≥98% (HPLC) 10MG ₹6016.2 2022-06-14 Buy
Sigma-Aldrich(India) SML2482 Ticagrelor ≥98% (HPLC) 50MG ₹12154.5 2022-06-14 Buy

Properties

Melting point :138-140°C
Boiling point :777.6±70.0 °C(Predicted)
Density :1.67
storage temp. :Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility :Methanol (Slightly)
pka :13.26±0.70(Predicted)
form :Solid
color :White to Off-White
Stability :Hygroscopic
InChIKey :OEKWJQXRCDYSHL-FNOIDJSQSA-N
SMILES :[C@@H]1(O)[C@@H](OCCO)C[C@@H](N2C3C(N=N2)=C(N[C@@H]2C[C@H]2C2=CC=C(F)C(F)=C2)N=C(SCCC)N=3)[C@@H]1O

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H411 Toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 2
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Ticagrelor is a reversible antagonist of the platelet purinergic P2Y12 receptor (Ki = 14 nM; IC50 = 1.8 μM), which is the main receptor responsible for ADP-induced platelet aggregation. It functions by directly changing the conformation of the P2Y12 receptor to inhibit ADP binding. Ticagrelor has been studied for its application in antiplatelet therapy to prevent ischemic cardiac complications associated with cardiovascular diseases.

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