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ChemicalBook > Product Catalogue >API >Antiallergic drugs >Antihistamines >Diphenhydramine Hydrochloride

Diphenhydramine Hydrochloride

Diphenhydramine Hydrochloride Structure
  • ₹2407.3 - ₹21300
  • Product name: Diphenhydramine Hydrochloride
  • CAS: 147-24-0
  • MF: C17H22ClNO
  • MW: 291.82
  • EINECS:205-687-2
  • MDL Number:MFCD00012479
  • Synonyms:2-(diphenylmethoxy)-n,n-dimethyl-ethanaminhydrochloride ;2-(diphenylmethoxy)-n,n-dimethyl-ethylaminhydrochloride ;alpha-Hydroxydiphenylmethane-beta-dimethylaminoethyl ether hydrochloride;alpha-hydroxydiphenylmethane-beta-dimethylaminoethyletherhydrochloride ;Benadril hydrochloride;Benadryl hydrochloride;Bena-fedrin;Bendylate
7 prices
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Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 1ML
  • 1G
  • 5G
  • 25G
  • 50G
  • 100G
  • 500G
  • ManufacturerTCI Chemicals (India)
  • Product numberD0423
  • Product descriptionDiphenhydramine Hydrochloride
  • Packaging25G
  • Price₹3300
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberD0423
  • Product descriptionDiphenhydramine Hydrochloride
  • Packaging500G
  • Price₹21300
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberD-015
  • Product descriptionDiphenhydramine hydrochloride solution 1.0?mg/mL in methanol (as free base), ampule of 1?mL, certified reference material, Cerilliant?
  • Packaging1ML
  • Price₹2407.3
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberD3630
  • Product descriptionDiphenhydramine hydrochloride ≥98% (HPLC)
  • Packaging5G
  • Price₹4633.1
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberD3630
  • Product descriptionDiphenhydramine hydrochloride ≥98% (HPLC)
  • Packaging50G
  • Price₹5336.73
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1015
  • Product descriptionDiphenhydramine hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging1G
  • Price₹8356.9
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberD3630
  • Product descriptionDiphenhydramine hydrochloride ≥98% (HPLC)
  • Packaging100G
  • Price₹9515.18
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) D0423 Diphenhydramine Hydrochloride 25G ₹3300 2022-05-26 Buy
TCI Chemicals (India) D0423 Diphenhydramine Hydrochloride 500G ₹21300 2022-05-26 Buy
Sigma-Aldrich(India) D-015 Diphenhydramine hydrochloride solution 1.0?mg/mL in methanol (as free base), ampule of 1?mL, certified reference material, Cerilliant? 1ML ₹2407.3 2022-06-14 Buy
Sigma-Aldrich(India) D3630 Diphenhydramine hydrochloride ≥98% (HPLC) 5G ₹4633.1 2022-06-14 Buy
Sigma-Aldrich(India) D3630 Diphenhydramine hydrochloride ≥98% (HPLC) 50G ₹5336.73 2022-06-14 Buy
Sigma-Aldrich(India) PHR1015 Diphenhydramine hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material 1G ₹8356.9 2022-06-14 Buy
Sigma-Aldrich(India) D3630 Diphenhydramine hydrochloride ≥98% (HPLC) 100G ₹9515.18 2022-06-14 Buy

Properties

Melting point :168-172 °C
Boiling point :163-167 °C(Press: 3 Torr)
Density :1.0489 (rough estimate)
refractive index :1.5800 (estimate)
Flash point :9℃
storage temp. :2-8°C
solubility :Very soluble in water, freely soluble in alcohol.
form :Crystalline Powder or Adhering Crystals
color :White
PH :pH(100g/L, 25℃) 4.0~5.5
Water Solubility :1000 g/L
Sensitive :Light Sensitive
Merck :14,3309
Stability :Stable, but slowly darkens upon exposure to light. Incompatible with strong oxidizing agents.
InChIKey :PCHPORCSPXIHLZ-UHFFFAOYSA-N
LogP :3.662 (est)
CAS DataBase Reference :147-24-0(CAS DataBase Reference)
NIST Chemistry Reference :diphenhydramine hydrochloride(147-24-0)
EPA Substance Registry System :Diphenhydramine hydrochloride (147-24-0)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:

Description

Diphenhydramine (DPH) is a first generation antihistamine which is a potent antagonist of the human H1 receptor (Ki = 11.7 nM). Like many first generation antihistamines, DPH readily crosses the blood-brain barrier and produces diverse cognitive and psychomotor effects. DPH also antagonizes muscarinic cholinergic receptors (Ki = 100 to 260 nM for M1 through M5), increasing the range of central nervous system effects and applications.

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