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1,3,5[10]-ESTRATRIENE-3,17BETA-DIOL 3-GLUCURONIDE SODIUM SALT

1,3,5[10]-ESTRATRIENE-3,17BETA-DIOL 3-GLUCURONIDE SODIUM SALT Structure
  • ₹24340 - ₹80840
  • Product name: 1,3,5[10]-ESTRATRIENE-3,17BETA-DIOL 3-GLUCURONIDE SODIUM SALT
  • CAS: 14982-12-8
  • MF: C24H31NaO8
  • MW: 470.49
  • EINECS:
  • MDL Number:MFCD00056552
  • Synonyms:3,17BETA-DIHYDROXY-1,3,5[10]-ESTRATRIENE 3-GLUCURONIDE SODIUM SALT;17BETA-ESTRADIOL 3-(BETA-D-GLUCURONIDE) SODIUM SALT;17-BETA-ESTRADIOL 3-GLUCURONIDE;1,3,5(10)-ESTRATRIEN-3,17-BETA-DIOL 3-GLUCOSIDURONATE, SODIUM SALT;1,3,5[10]-ESTRATRIENE-3,17BETA-DIOL 3-GLUCURONIDE SODIUM SALT;17B-estradiol 3-(B-D-glucuronide)*sodium;oestradiol 3-(beta-D-glucuronide), sodium salt;1,3,5(10)-Estratriene-3,17β-diol 3-glucuronide, 3,17β-Dihydroxy-1,3,5(10)-estratriene 3-glucuronide
Price3 Properties Safety Information Description
3 prices
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Brand

  • Sigma-Aldrich(India)

Package

  • 5MG
  • 10MG
  • 25MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberE2127
  • Product descriptionβ-Estradiol 3-(β-D-glucuronide) sodium salt
  • Packaging5MG
  • Price₹24340
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberE2127
  • Product descriptionβ-Estradiol 3-(β-D-glucuronide) sodium salt
  • Packaging10MG
  • Price₹42830
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberE2127
  • Product descriptionβ-Estradiol 3-(β-D-glucuronide) sodium salt
  • Packaging25MG
  • Price₹80840
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) E2127 β-Estradiol 3-(β-D-glucuronide) sodium salt 5MG ₹24340 2022-06-14 Buy
Sigma-Aldrich(India) E2127 β-Estradiol 3-(β-D-glucuronide) sodium salt 10MG ₹42830 2022-06-14 Buy
Sigma-Aldrich(India) E2127 β-Estradiol 3-(β-D-glucuronide) sodium salt 25MG ₹80840 2022-06-14 Buy

Properties

storage temp. :−20°C
solubility :≤20mg/ml in DMSO;10mg/ml in dimethyl formamide
form :crystalline solid
Stability :Hygroscopic

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

Description

Estradiol 3-(β-D-glucuronide) (E23G) is a non-cholestatic regioisomer of the estrogen metabolite, estradiol 17-(β-D-glucuronide) (E217G; ). It acts as a substrate for multidrug resistance protein 2 (MRP2; Km = 122 μM), competing with E217G for MRP2-mediated transport (IC50 = 14.2 μM). E23G has been reported to inhibit E217G transport through rat organic anion-transporting polypeptide 1 with a Ki value of 9.7 μM, but is a low-affinity inhibitor of both MRP4 and MRP7 (IC50s = ~ 100 μM).

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