Melting point :178-179 °C(lit.)
alpha :D25 +76 to +83° (dioxane)
Boiling point :355.44°C (rough estimate)
Density :1.0708 (rough estimate)
refractive index :80.4 ° (C=1, Dioxane)
Flash point :2℃
storage temp. :room temp
solubility :Practically insoluble in water, soluble in acetone, sparingly soluble in ethanol (96 per cent), slightly soluble in methylene chloride.
pka :pKa 10.71±0.02(H2O(0.1% p-dioxane) t=25±0.1 I=0.03(KCl))(Approximate)
form :powder
color :White to off-white
Water Solubility :Soluble in dimethyl sulfoxide, ethanol , water, phosphate buffer saline, dimethyl formamide, acetone, dioxane and alkali hydroxides. Slightly soluble in vegetable oils.
Merck :14,3703
BRN :1914275
BCS Class :1
Stability :Stable. Incompatible with strong oxidizing agents.
InChIKey :VOXZDWNPVJITMN-ZBRFXRBCSA-N
CAS DataBase Reference :50-28-2(CAS DataBase Reference)
NIST Chemistry Reference :Estra-1,3,5(10)-triene-3,17beta-diol(50-28-2)
EPA Substance Registry System :Estradiol (50-28-2)

Symbol(GHS):
Signal word:	Danger
Hazard statements:	Code Hazard statements Hazard class Category Signal word Pictogram P-Codes H351 Suspected of causing cancer Carcinogenicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501 H362 May cause harm to breast-fed children Reproductive toxicity, effects on or via lactation Additional category P201, P260, P263, P264, P270,P308+P313 H410 Very toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 1 Warning P273, P391, P501
Precautionary statements:	P202 Do not handle until all safety precautions have been read and understood. P260 Do not breathe dust/fume/gas/mist/vapours/spray. P263 Avoid contact during pregnancy/while nursing. P264 Wash hands thoroughly after handling. P264 Wash skin thouroughly after handling. P273 Avoid release to the environment. P308+P313 IF exposed or concerned: Get medical advice/attention.