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ChemicalBook > Product Catalogue >API >Antibiotics >Other antibiotic Drugs >Estradiol

Estradiol

Estradiol Structure
  • ₹10576.03 - ₹74898.18
  • Product name: Estradiol
  • CAS: 57-91-0
  • MF: C18H24O2
  • MW: 272.39
  • EINECS:200-354-8
  • MDL Number:MFCD00064144
  • Synonyms:1,3,5-estratriene-3,17-alpha-diol ;1,3,5-Estratriene-3,17alpha-diol;17alpha-Oestradiol;3,17alpha-Dihydroxyestra-1,3,5(10)-triene;3,17-alpha-dihydroxyoestra-1,3,5(10)-triene ;3,17alpha-Dihydroxyoestra-1,3,5(10)-triene;5(10)-triene-3,17-diol,(17-alpha)-estra-3 ;epiestradial
5 prices
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Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 100MG
  • 500MG
  • 1G
  • ManufacturerTCI Chemicals (India)
  • Product numberE0919
  • Product descriptionα-Estradiol min. 98.0 %
  • Packaging1G
  • Price₹20800
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberE8750
  • Product descriptionα-Estradiol powder, ≥98% (TLC)
  • Packaging100MG
  • Price₹10576.03
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number46542
  • Product descriptionα-Estradiol VETRANAL?, analytical standard
  • Packaging100MG
  • Price₹12784.33
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberE8750
  • Product descriptionα-Estradiol powder, ≥98% (TLC)
  • Packaging500MG
  • Price₹41568
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberE8750
  • Product descriptionα-Estradiol powder, ≥98% (TLC)
  • Packaging1G
  • Price₹74898.18
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) E0919 α-Estradiol min. 98.0 % 1G ₹20800 2022-05-26 Buy
Sigma-Aldrich(India) E8750 α-Estradiol powder, ≥98% (TLC) 100MG ₹10576.03 2022-06-14 Buy
Sigma-Aldrich(India) 46542 α-Estradiol VETRANAL?, analytical standard 100MG ₹12784.33 2022-06-14 Buy
Sigma-Aldrich(India) E8750 α-Estradiol powder, ≥98% (TLC) 500MG ₹41568 2022-06-14 Buy
Sigma-Aldrich(India) E8750 α-Estradiol powder, ≥98% (TLC) 1G ₹74898.18 2022-06-14 Buy

Properties

Melting point :176-180 °C(lit.)
Boiling point :355.44°C (rough estimate)
alpha :D20 +53 to +56° (c = 0.9 in dioxane)
Density :1.0708 (rough estimate)
refractive index :1.4800 (estimate)
storage temp. :Sealed in dry,Room Temperature
solubility :ethanol: 50 mg/mL, clear, colorless
form :powder
pka :10.27±0.60(Predicted)
color :white with slight yellow
Water Solubility :3.9mg/L(25 ºC)
Merck :14,3704
CAS DataBase Reference :57-91-0(CAS DataBase Reference)
NIST Chemistry Reference :Estra-1,3,5(10)-triene-3,17alpha-diol(57-91-0)
EPA Substance Registry System :Estra-1,3,5(10)-triene-3,17-diol, (17.alpha.)- (57-91-0)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H341 Suspected of causing genetic defects Germ cell mutagenicity Category 2 Warning P201,P202, P281, P308+P313, P405,P501
H351 Suspected of causing cancer Carcinogenicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
H362 May cause harm to breast-fed children Reproductive toxicity, effects on or via lactation Additional category P201, P260, P263, P264, P270,P308+P313
H410 Very toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 1 Warning GHS hazard pictograms P273, P391, P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P263 Avoid contact during pregnancy/while nursing.
P273 Avoid release to the environment.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

α-Estradiol is an endogenous ligand for estrogen receptors ERα (Ki = 0.2 nM) and ERβ (Ki = 1.2 nM). Studies indicate that α-Estradiol is a short acting estrogen which only forms complexes with estrogen ligand receptors for a short period of time. These studies suggest that α-estradiol is beneficial in studying the affects caused by the MAPK signaling cascade such as cell division, neuronal differentiation, and neuronal survival in the developing brain. Furthermore, α-estradiol inhibits the influx of calcium in human aortic smooth muscle cells.

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