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5(6)-(N-SUCCINIMIDYLOXYCARBONYL)-3',6',O,O'-DIACETYLFLUORESCEIN

5(6)-(N-SUCCINIMIDYLOXYCARBONYL)-3',6',O,O'-DIACETYLFLUORESCEIN Structure
  • ₹38184 - ₹105527.7
  • Product name: 5(6)-(N-SUCCINIMIDYLOXYCARBONYL)-3',6',O,O'-DIACETYLFLUORESCEIN
  • CAS: 150347-59-4
  • MF: C29H19NO11
  • MW: 557.46
  • EINECS:
  • MDL Number:MFCD31812843
  • Synonyms:CARBOXYFLUORESCEIN DIACETATE, NHS ESTER;5(6)-CARBOXYFLUORESCEIN DIACETATE-N-HYDROXY-SUCCINIMIDE ESTER;5(6)-CARBOXYFLUORESCEIN DIACETATE N-SUCCINIMIDYL ESTER;5-CARBOXYFLUORESCEIN-NHS DIACETATE;5-CARBOXY-DI-O-ACETYLFLUORESCEIN N-SUCCINIMIDYL ESTER;5-CARBOXYFLUORESCEIN DIACETATE-N-HYDROXYSUCCINIMIDE ESTER;5-CARBOXY-FLUORESCEIN DIACETATE N-SUCCINIMIDYL ESTER;5-FAM-NHS DIACETATE
2 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 25MG
  • 100MG
  • ManufacturerSigma-Aldrich(India)
  • Product number21888
  • Product description5(6)-Carboxyfluorescein diacetate N-succinimidyl ester BioReagent, suitable for fluorescence, ≥90% (HPLC)
  • Packaging25MG
  • Price₹38184
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number21888
  • Product description5(6)-Carboxyfluorescein diacetate N-succinimidyl ester BioReagent, suitable for fluorescence, ≥90% (HPLC)
  • Packaging100MG
  • Price₹105527.7
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) 21888 5(6)-Carboxyfluorescein diacetate N-succinimidyl ester BioReagent, suitable for fluorescence, ≥90% (HPLC) 25MG ₹38184 2022-06-14 Buy
Sigma-Aldrich(India) 21888 5(6)-Carboxyfluorescein diacetate N-succinimidyl ester BioReagent, suitable for fluorescence, ≥90% (HPLC) 100MG ₹105527.7 2022-06-14 Buy

Properties

Melting point :152-154 °C(lit.)
storage temp. :-20°C
solubility :DMF: soluble
pka :6.45(at 25℃)
form :Solid
color :Off-white to yellow
PH Range :Weak green ' uorescence (6.0) to strong green ' uorescence (7.2)
λmax :<300nm
Major Application :Diagnosis of cancer, restricting HIV replication, antiinflammatory agent, detecting bacteria, cell proliferation assays
InChIKey :QSWYNOQSGMUDQZ-UHFFFAOYSA-N

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

5(6)-CFDA-SE is a stable, cell-permeable dye that consists of a fluorescein molecule containing two acetate moieties and a SE functional group. Upon diffusion into the intracellular environment, the acetate groups are removed by cellular esterases, rendering the dye highly fluorescent and no longer permeant to the cell membrane. CFDA-SE is often employed to assay cell proliferation as it is partitioned with high fidelity between daughter cells for up to eight generational divisions.

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