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Difluoromethyl phenyl sulfone

Difluoromethyl phenyl sulfone Structure
  • ₹4300 - ₹45345.93
  • Product name: Difluoromethyl phenyl sulfone
  • CAS: 1535-65-5
  • MF: C7H6F2O2S
  • MW: 192.18
  • EINECS:
  • MDL Number:MFCD01050170
  • Synonyms:Difluoromethyl phenyl sulfone;1-(difluoroMethylsulfonyl)benzene;Benzene, [(difluoroMethyl)sulfonyl]-;Difluoromethyl phenyl sulfone >=97%;Phenyl difluoromethyl sulfone;Difluoromethyl Phenyl Sulfone >Difluoromethylphenylsulfone,95%;Difluoromethyl phenyl sul
4 prices
Selected condition:

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 1G
  • 5G
  • 10G
  • ManufacturerTCI Chemicals (India)
  • Product numberD4764
  • Product descriptionDifluoromethyl Phenyl Sulfone min. 98.0 %
  • Packaging1G
  • Price₹4300
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberD4764
  • Product descriptionDifluoromethyl Phenyl Sulfone min. 98.0 %
  • Packaging5G
  • Price₹20700
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number742600
  • Product descriptionDifluoromethyl phenyl sulfone ≥97%
  • Packaging1G
  • Price₹5542.4
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number742600
  • Product descriptionDifluoromethyl phenyl sulfone ≥97%
  • Packaging10G
  • Price₹45345.93
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) D4764 Difluoromethyl Phenyl Sulfone min. 98.0 % 1G ₹4300 2022-05-26 Buy
TCI Chemicals (India) D4764 Difluoromethyl Phenyl Sulfone min. 98.0 % 5G ₹20700 2022-05-26 Buy
Sigma-Aldrich(India) 742600 Difluoromethyl phenyl sulfone ≥97% 1G ₹5542.4 2022-06-14 Buy
Sigma-Aldrich(India) 742600 Difluoromethyl phenyl sulfone ≥97% 10G ₹45345.93 2022-06-14 Buy

Properties

Melting point :24-25℃
Boiling point :115-120 °C(Press: 7 Torr)
Density :1.348
refractive index :1.5000
Flash point :128℃
storage temp. :under inert gas (nitrogen or Argon) at 2–8 °C
solubility :Chloroform (Slightly), Methanol (Slightly)
form :liquid
color :colorless
Water Solubility :Soluble in chloroform and water.
BRN :2259218

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.

Description

Used as a reagent for the nucleophilic difluoro(phenylsulfonyl)methylation of carbonyls and fluorination. Reagent used for reductive silylation and the preparation of trifluoro- and difluoromethylsilanes by reductive coupling of fluoromethyl sulfones, sulfoxides and sulfides with chlorosilanes, fluoroalkylation/chloroalkylation of α,β-enones, arynes, acetylenic ketones and other Michael acceptors, difluoromethylation of primary alkyl halides via nucleophilic substitution-reductive desulfonylation. Also used as reagent in preparation of α-difluoromethyl amines via stereo selective (phenylsulfonyl)difluoromethylation of chiral sulfinyl aldimines and Anti-difluoropropanediols via potassium tert-butoxide-catalyzed difluoromethylenation of aldehydes.

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