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ChemicalBook > Product Catalogue >Pharmaceutical intermediates >Heterocyclic compound >Pyran compounds >tert-Butyl 2-cyanopiperidine-1-carboxylate

tert-Butyl 2-cyanopiperidine-1-carboxylate

tert-Butyl 2-cyanopiperidine-1-carboxylate Structure
  • ₹10088.9
  • Product name: tert-Butyl 2-cyanopiperidine-1-carboxylate
  • CAS: 153749-89-4
  • MF: C11H18N2O2
  • MW: 210.27
  • EINECS:
  • MDL Number:MFCD01861221
  • Synonyms:(+/-)-1-N-BOC-2-CYANO-PIPERIDINE;1-N-BOC-2-CYANO-PIPERIDINE;2-CYANO-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER;TERT-BUTYL2-CYANOPIPERIDINE-1-CARBOXYLATE;1-Piperidinecarboxylic acid, 2-cyano-, 1,1-dimethylethyl ester;1-N-BOC-2-CYANOPIPERDINE;1-BOC-2-CYANOPIPERIDINE 98+%;1-tert-Butoxycarbonyl-2-cyanopiperidine
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Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 1G
  • ManufacturerSigma-Aldrich(India)
  • Product number735701
  • Product description1-Boc-piperidine-2-carbonitrile 95%
  • Packaging1G
  • Price₹10088.9
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) 735701 1-Boc-piperidine-2-carbonitrile 95% 1G ₹10088.9 2022-06-14 Buy

Properties

Melting point :62-67℃
Boiling point :325.3±35.0 °C(Predicted)
Density :1.07±0.1 g/cm3(Predicted)
storage temp. :2-8°C
pka :-4.85±0.40(Predicted)
form :Powder
color :White to pale brown
InChIKey :LKAJZBMOVZIKHA-UHFFFAOYSA-N
CAS DataBase Reference :153749-89-4(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.

Description

Tert-Butyl 2-cyanopiperidine-1-carboxylate is an enantioselective organometallic compound. It is a nitrile that reacts with electrophiles such as Grignard reagents and cyano to form an anion. This compound has two chiral centers, each of which can assume either the R or S configuration. The enantiomeric purity of tert-butyl 2-cyanopiperidine-1-carboxylate is greater than 99%. This compound has a low melting point and a half life of about 10 h in water, which makes it stable for use in organic synthesis. It is commonly used in science as a chiral auxiliary in asymmetric synthesis and as a catalyst for the conversion of epoxides to alcohols.

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