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ChemicalBook > Product Catalogue >Biochemical Engineering >Inhibitors >GPCR & G Protein >CXCR antagonist >Plerixafor 8HCl (AMD3100 8HCl)

Plerixafor 8HCl (AMD3100 8HCl)

Plerixafor 8HCl (AMD3100 8HCl) Structure
  • ₹9380 - ₹14970
  • Product name: Plerixafor 8HCl (AMD3100 8HCl)
  • CAS: 155148-31-5
  • MF: C28H54N8
  • MW: 502.78
  • EINECS:828-184-5
  • MDL Number:MFCD04974488
  • Synonyms:SID791;AMD3100;BISCYCLAM;JM3100;AMD3100 OCTAHYDROCHLORIDE HYDRATE ANHYDROUS;amd3100 octahydrochloride hydrate;1,1'-[1,4-Phenylenebis-(methylene)]-bis-(1,4,8,11-tetraazacyclotetradecane) octahydrochloride, min. 95 % (NMR);AMD3100 hydrate octahydrochloride
5 prices
Selected condition:

Brand

  • Sigma-Aldrich
  • Sigma-Aldrich(India)

Package

  • 5MG
  • 15MG
  • ManufacturerSigma-Aldrich
  • Product number239820
  • Product descriptionCXCR4 Antagonist I, AMD3100 - CAS 155148-31-5 - Calbiochem The CXCR4 Antagonist I, AMD3100, also referenced under CAS 155148-31-5, controls the biological activity of CXCR4. This small molecule/inhibitor is primarily used for Cell Signaling applications.
  • Packaging5MG
  • Price₹9380
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number239825
  • Product descriptionInSolution CXCR4 Antagonist I, AMD3100 - CAS 155148-31-5 - Calbiochem InSolution CXCR4 Antagonist I, AMD3100, CAS 155148-31-5, is a 50 mM (15 mg/308 μL) solution of CXCR4 Antagonist I, AMD3100 (Cat. No. 239820) in H?O.
  • Packaging15MG
  • Price₹14970
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number239820
  • Product descriptionCXCR4 Antagonist I, AMD3100 - CAS 155148-31-5 - Calbiochem The CXCR4 Antagonist I, AMD3100, also referenced under CAS 155148-31-5, controls the biological activity of CXCR4. This small molecule/inhibitor is pr
  • Packaging5MG
  • Price₹9380
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberA5602
  • Product descriptionAMD3100 octahydrochloride hydrate ≥97% (NMR), solid
  • Packaging5MG
  • Price₹12427.1
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number239825
  • Product descriptionInSolution CXCR4 Antagonist I, AMD3100 - CAS 155148-31-5 - Calbiochem InSolution CXCR4 Antagonist I, AMD3100, CAS 155148-31-5, is a 50 mM (15 mg/308 μL) solution of CXCR4 Antagonist I, AMD3100 (Cat. No. 239820) in H?O.
  • Packaging15MG
  • Price₹14970
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich 239820 CXCR4 Antagonist I, AMD3100 - CAS 155148-31-5 - Calbiochem The CXCR4 Antagonist I, AMD3100, also referenced under CAS 155148-31-5, controls the biological activity of CXCR4. This small molecule/inhibitor is primarily used for Cell Signaling applications. 5MG ₹9380 2022-06-14 Buy
Sigma-Aldrich 239825 InSolution CXCR4 Antagonist I, AMD3100 - CAS 155148-31-5 - Calbiochem InSolution CXCR4 Antagonist I, AMD3100, CAS 155148-31-5, is a 50 mM (15 mg/308 μL) solution of CXCR4 Antagonist I, AMD3100 (Cat. No. 239820) in H?O. 15MG ₹14970 2022-06-14 Buy
Sigma-Aldrich(India) 239820 CXCR4 Antagonist I, AMD3100 - CAS 155148-31-5 - Calbiochem The CXCR4 Antagonist I, AMD3100, also referenced under CAS 155148-31-5, controls the biological activity of CXCR4. This small molecule/inhibitor is pr 5MG ₹9380 2022-06-14 Buy
Sigma-Aldrich(India) A5602 AMD3100 octahydrochloride hydrate ≥97% (NMR), solid 5MG ₹12427.1 2022-06-14 Buy
Sigma-Aldrich(India) 239825 InSolution CXCR4 Antagonist I, AMD3100 - CAS 155148-31-5 - Calbiochem InSolution CXCR4 Antagonist I, AMD3100, CAS 155148-31-5, is a 50 mM (15 mg/308 μL) solution of CXCR4 Antagonist I, AMD3100 (Cat. No. 239820) in H?O. 15MG ₹14970 2022-06-14 Buy

Properties

Melting point :188 - 193°C (dec.)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :H2O: ≥10 mg/mL, clear
form :solid
color :White
Water Solubility :Soluble in water (100mM)
Stability :Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20°C for up to 2 months.

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H226 Flammable liquid and vapour Flammable liquids Category 3 Warning
H314 Causes severe skin burns and eye damage Skin corrosion/irritation Category 1A, B, C Danger GHS hazard pictograms P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233 Keep container tightly closed.
P240 Ground/bond container and receiving equipment.
P241 Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242 Use only non-sparking tools.
P243 Take precautionary measures against static discharge.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P330+P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P363 Wash contaminated clothing before reuse.
P370+P378 In case of fire: Use … for extinction.
P403+P235 Store in a well-ventilated place. Keep cool.
P405 Store locked up.

Description

AMD3100 octahydrochloride is a selective bicyclam derivative which functions as a stem cell mobiliser via blocking the CXCR4 chemokine receptor. Studies suggest that AMD3100 octahydrochloride causes the rapid movement of stem cells out of bone marrow via blocking the CXCR4 receptor. Since the CXCR4 receptor is responsible for regulating metastasis in chemoresistant melanoma cells, blocking this receptor can possibly reduce the metastasis of melanoma cells. In addition, studies indicate that AMD3100 octahydrochloride can inhibit the replication of human immunodeficiency virus in vitro by blocking the entry of the virus into cells. Furthermore, AMD3100 octahydrochloride can also reduce the number of human CD4+ T cells.

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