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15(S)-HPETE

15(S)-HPETE Structure
  • ₹43430
  • Product name: 15(S)-HPETE
  • CAS: 70981-96-3
  • MF: C20H32O4
  • MW: 336.47
  • EINECS:633-223-2
  • MDL Number:MFCD00063577
  • Synonyms:15(S)-HPETE;15(S)-hydroperoxy-(5Z,8Z,11Z,13E)-*eicosatetraeno;15(S)-HYDROPEROXY-(5Z,8Z,11Z,13E)-*EICOS ATETRAENOIC;15(S)-HYDROPEROXY-(5Z,8Z,11Z,13E)-EICOSATETRAENOIC ACID (2MG/ML ETHANOL SOLUTION);15-Hydroxyeicosa-5Z,8Z,11Z,13E-tetraenoic acid;(S-(E,Z,Z,Z))-15-Hydroperoxy-5,8,11,13-eicosatetraenoic acid;5,8,11,13-Eicosatetraenoic acid, 15-hydroperoxy-, (S-(E,Z,Z,Z))-;15(S)-HpETE Lipid Maps MS Standard
Price1 Properties Safety Information Description
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Brand

  • Sigma-Aldrich(India)

Package

  • 50μG
  • ManufacturerSigma-Aldrich(India)
  • Product numberH9521
  • Product description15(S)-Hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoic acid ~100?μg/mL in ethanol, ≥95%
  • Packaging50μG
  • Price₹43430
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) H9521 15(S)-Hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoic acid ~100?μg/mL in ethanol, ≥95% 50μG ₹43430 2022-06-14 Buy

Properties

Flash point :14 °C
storage temp. :−70°C
solubility :0.1 M Na2CO3: 2 mg/ml; DMF: Miscible; DMSO: Miscible; Ethanol: Miscible; PBS pH 7.2: 0.8 mg/ml

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger GHS hazard pictograms P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P403+P235 Store in a well-ventilated place. Keep cool.

Description

15(S)-HpETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of 15-lipoxygenase (15-LO) on arachidonic acid. It is either metabolized to 14,15-leukotriene A4 or reduced to 15(S)-HETE by peroxidases. 15(S)-HpETE mediates a number of biological functions including the induction of c-fos and c-jun, and activation of AP-1. 15(S)-HpETE inhibits prostacyclin synthesis in porcine aortic microsomes and bovine endothelial cells, and can cause the suicide inactivation of porcine 12-LO.

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