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(S)-3,5-DIHYDROXYPHENYLGLYCINE

(S)-3,5-DIHYDROXYPHENYLGLYCINE Structure
  • ₹25460.4 - ₹49210.45
  • Product name: (S)-3,5-DIHYDROXYPHENYLGLYCINE
  • CAS: 162870-29-3
  • MF: C8H9NO4
  • MW: 183.16
  • EINECS:2017-001-1
  • MDL Number:MFCD00673763
  • Synonyms:(S)-3,5-DIHYDROXYPHENYLGLYCINE;(S)-3,5-DHPG;S-DHPG;(S)-3,5-Dihydroxyphenylglycine hydrate;+-2,5-DIMETHOXY-4-IODOAMPHETAMINE HYDROCHLORIDE;(S)-3,5-Dihydroxylphenylglycine ;Benzeneacetic acid, α-amino-3,5-dihydroxy-, (αS)-;(2S)-2-amino-2-(3,5-dihydroxyphenyl)acetic acid
Price2 Properties Safety Information Description
2 prices
Selected condition：

Brand

  • Sigma-Aldrich(India)

Package

  • 5MG
  • 10MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberD3689
  • Product description(S)-3,5-Dihydroxyphenylglycine hydrate ≥98% (HPLC), powder
  • Packaging5MG
  • Price₹25460.4
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberD3689
  • Product description(S)-3,5-Dihydroxyphenylglycine hydrate ≥98% (HPLC), powder
  • Packaging10MG
  • Price₹49210.45
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) D3689 (S)-3,5-Dihydroxyphenylglycine hydrate ≥98% (HPLC), powder 5MG ₹25460.4 2022-06-14 Buy
Sigma-Aldrich(India) D3689 (S)-3,5-Dihydroxyphenylglycine hydrate ≥98% (HPLC), powder 10MG ₹49210.45 2022-06-14 Buy

Properties

Melting point :>207°C (dec.)
Boiling point :448.8±33.0 °C(Predicted)
Density :1.550±0.06 g/cm3(Predicted)
storage temp. :−20°C
solubility :Aqueous Base (Very Slightly, Sonicated), Methanol (Slightly), Water (Slightly, Heated)
pka :1.77±0.10(Predicted)
form :solid
color :white
Water Solubility :Soluble to 50 mM in water
Stability :Hygroscopic

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

(S)-3,5-DHPG, known more commonly as DHPG, is an agonist of the group I metabotropic glutamate receptors (mGluRs), binding both mGluR1a and mGluR5a (Ki = 0.9 and 3.9 μM, respectively) but not ionotropic glutamate receptors. The (S)-enantiomer is about ten times more potent than the (R)-enantiomer. (S)-3,5-DHPG is commonly used to evaluate the roles of group I mGluRs in neuronal signaling.

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