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1-[2-CHLORO-6-[[(3-IODOPHENYL)METHYL]AMINO]-9H-PURIN-9-YL]-1-DEOXY-N-METHYL-BETA-D-RIBOFURANURONAMIDE

1-[2-CHLORO-6-[[(3-IODOPHENYL)METHYL]AMINO]-9H-PURIN-9-YL]-1-DEOXY-N-METHYL-BETA-D-RIBOFURANURONAMIDE Structure
  • ₹5300 - ₹274749.33
  • Product name: 1-[2-CHLORO-6-[[(3-IODOPHENYL)METHYL]AMINO]-9H-PURIN-9-YL]-1-DEOXY-N-METHYL-BETA-D-RIBOFURANURONAMIDE
  • CAS: 163042-96-4
  • MF: C18H18ClIN6O4
  • MW: 544.73
  • EINECS:
  • MDL Number:MFCD01861178
  • Synonyms:2-CL-IB-MECA;1-[2-CHLORO-6-[[(3-IODOPHENYL)METHYL]AMINO]-9H-PURIN-9-YL]-1-DEOXY-N-METHYL-BETA-D-RIBOFURANURONAMIDE;1-(2-Chloro-6-(((3-iodophenyl)methyl)amino)-(9H)-purin-9-yl)-1-deoxy-N-methyl-beta-D-ribofuranuronamide;Cl-IB-MECA, 2-Chloro-N6-(3-iodobenzyl)-adenosine-5μ-N-methyluronamide;1-[2-Chloro-6-[[(3-iodophenyl)methyl]amino]-9H-purin-9-yl]-1-deoxy-N-methyl-β-D-ribofuranuronamide;1-[2-CHLORO-6-[[(3-IODOPHENYL)METHYL]AMINO]-9H-PURIN-9-YL]-1-DEOXY-N-METHYL-β-D-RIBOFURANURONAMIDE 2-Cl-IB-Meca;b-D-RibofuranuronaMide,1-[2-chloro-6-[[(3-iodophenyl)Methyl]aMino]-9H-purin-9-yl]-1-deoxy-N-Methyl-;(2S,3S,4R,5R)-5-(2-Chloro-6-((3-iodobenzyl)aMino)-9H-purin-9-yl)-3,4-dihydroxy-N-Methyltetrahydrofuran-2-carboxaMide
4 prices
Selected condition:

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 5MG
  • 10MG
  • 25MG
  • 50MG
  • ManufacturerTCI Chemicals (India)
  • Product numberC3601
  • Product descriptionChloro-IB-MECA
  • Packaging10MG
  • Price₹5300
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberC3601
  • Product descriptionChloro-IB-MECA
  • Packaging50MG
  • Price₹9800
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberC277
  • Product descriptionChloro-IB-MECA solid, ≥98% (HPLC)
  • Packaging5MG
  • Price₹72159.45
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberC277
  • Product descriptionChloro-IB-MECA solid, ≥98% (HPLC)
  • Packaging25MG
  • Price₹274749.33
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) C3601 Chloro-IB-MECA 10MG ₹5300 2022-05-26 Buy
TCI Chemicals (India) C3601 Chloro-IB-MECA 50MG ₹9800 2022-05-26 Buy
Sigma-Aldrich(India) C277 Chloro-IB-MECA solid, ≥98% (HPLC) 5MG ₹72159.45 2022-06-14 Buy
Sigma-Aldrich(India) C277 Chloro-IB-MECA solid, ≥98% (HPLC) 25MG ₹274749.33 2022-06-14 Buy

Properties

Melting point :209 °C
Density :2.04±0.1 g/cm3 (20 ºC 760 Torr)
storage temp. :Keep in dark place,Inert atmosphere,2-8°C
solubility :DMSO: >20mg/mL
form :solid
pka :12.68±0.70(Predicted)
color :white

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Chloro-IB-MECA is an Adenosine A3-R agonist with a Ki value of 0.33 nM. Chloro-IB-MECA displays 2500 and 1400-fold selectivity over Adenosine A1-R and Adenosine A2A-R, respectively. This explains selectivity over the Na+-independent adenosine transporter.

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