(R)-N- (4-(chlorodifluoromethoxy)phenyl)- 6-(3- hydroxypyrrolidin-1- yl)-5- (1H-pyrazol- 5-yl)nicotinamide
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- ₹0
- Product name: (R)-N- (4-(chlorodifluoromethoxy)phenyl)- 6-(3- hydroxypyrrolidin-1- yl)-5- (1H-pyrazol- 5-yl)nicotinamide
- CAS: 1492952-76-7
- MF: C20H18ClF2N5O3
- MW: 449.84
- EINECS:
- MDL Number:MFCD31560488
- Synonyms:(R)-N- (4-(chlorodifluoromethoxy)phenyl)- 6-(3- hydroxypyrrolidin-1- yl)-5- (1H-pyrazol- 5-yl)nicotinamide;ABL-001;ABL001;ABL-001;ABL-001; AB -001; ABL001; ASCIMINIB; ASCIMINIB FREE BASE;;asciminib free base;(R)-N- (4-(CHLORODIFLUOROMETHOXY)PHENYL)- 6-(3- HYDROXYPYRROLIDIN-1- YL)-5- (1H-PYRAZOL- 5-YL)NICOTI;EOS-61420;L1F3R18W77
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Properties
Boiling point :631.7±55.0 °C(Predicted)
Density :1.518±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO:93.0(Max Conc. mg/mL);206.74(Max Conc. mM)
Ethanol:90.0(Max Conc. mg/mL);200.07(Max Conc. mM) form :A crystalline solid
pka :10.81±0.70(Predicted)
color :White to off-white
Density :1.518±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO:93.0(Max Conc. mg/mL);206.74(Max Conc. mM)
Ethanol:90.0(Max Conc. mg/mL);200.07(Max Conc. mM) form :A crystalline solid
pka :10.81±0.70(Predicted)
color :White to off-white
Safety Information
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Signal word: | Warning | |||||||||||||||||||||||||||||||||||
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Description
Asciminib comprises ABL kinase inhibitors and/or SLC7A11 inhibitors for the treatment of cancer and central nervous system (CNS) disorders.Related product price
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