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4-Chloro-8-methoxyquinoline

4-Chloro-8-methoxyquinoline Structure
  • ₹23944.9
  • Product name: 4-Chloro-8-methoxyquinoline
  • CAS: 16778-21-5
  • MF: C10H8ClNO
  • MW: 193.63
  • EINECS:632-643-3
  • MDL Number:MFCD00033679
  • Synonyms:4-CHLORO-8-METHOXYQUINOLINE;8-Methoxy-4-chloro quinoline;4-Chloro-8-Methoxyquinoline;Quinoline, 4-chloro-8-methoxy-
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Brand

  • Sigma-Aldrich(India)

Package

  • 1G
  • ManufacturerSigma-Aldrich(India)
  • Product numberBBO000177
  • Product description4-Chloro-8-methoxyquinoline AldrichCPR
  • Packaging1G
  • Price₹23944.9
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) BBO000177 4-Chloro-8-methoxyquinoline AldrichCPR 1G ₹23944.9 2022-06-14 Buy

Properties

Melting point :79-80 °C
Boiling point :299.9±20.0 °C(Predicted)
Density :1.267±0.06 g/cm3(Predicted)
storage temp. :-20°C Freezer
solubility :Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form :Solid
pka :1.86±0.30(Predicted)
color :Off-White to Pale Green
InChIKey :LCYDNBWXXPOMQL-UHFFFAOYSA-N

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger GHS hazard pictograms P280, P305+P351+P338, P310
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

4-Chloro-8-methoxyquinoline is a quinoline compound substituted with both a chloro and a methoxy group. This substituted heterocycle is potentially useful as a building block for synthesis, where both the chloro and methoxy groups may serve as functional sites for elaboration. 4-Chloro-8-methoxyquinoline has been reported in the synthesis of other chloromethoxyquinolines towards the synthesis of substituted 4-aminoquinoline antimalarial compounds. 4-Chloro-8-methoxyquinoline has also been described as a starting material in the synthesis of potent CRTh2(DP2) receptor antagonists.

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